Mesci Aruz, Wong Rebecca Ks
Department of Radiation Oncology, Princess Margaret Cancer Center, University Health Network, University of Toronto, Toronto, Ontario, Canada.
J Surg Oncol. 2022 Jun;125(7):1161-1175. doi: 10.1002/jso.26880.
Gastric cancers are heterogeneous. There are important differences between gastric and junctional tumors and a focus on evidence based on true gastric cancers is important to guide treatment decision and the design of innovative strategies. We present key evidence shaping the current use of radiotherapy, discuss technical radiotherapy considerations that are important to consider in multidisciplinary decision-making, and highlight selected research strategies including radiotherapeutic advances, theranostic approaches and key ongoing clinical trials to watch that will shape the role of radiotherapy in gastric cancers for the future.
胃癌具有异质性。胃癌与交界性肿瘤之间存在重要差异，关注基于真正胃癌的证据对于指导治疗决策和创新策略的设计至关重要。我们展示了影响当前放疗应用的关键证据，讨论了在多学科决策中需要考虑的重要放疗技术因素，并强调了选定的研究策略，包括放疗进展、诊疗方法以及值得关注的关键正在进行的临床试验，这些将塑造放疗在未来胃癌治疗中的作用。
