Vidal José E, Rivero René L M, Dos Santos Sigrid de Sousa, Guedes Bruno F, Gomes Hélio R, de Oliveira Augusto C Penalva, Garcia Hector H
Departamento de Neurologia, Instituto de Infectologia Emílio Ribas, São Paulo, Brazil.
Departamento de Moléstias Infecciosas e Parasitárias, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Am J Trop Med Hyg. 2022 Mar 7;106(5):1426-33. doi: 10.4269/ajtmh.21-1175.
Perilesional edema, associated or not with neurological manifestations, is a well-characterized finding in cases of calcified neurocysticercosis. There are no previous reports of HIV-related calcified toxoplasmosis that mimics this presentation of neurocysticercosis. We report on five patients, four of them with new-onset neurological manifestations, who showed brain calcifications associated with perilesional edema. All cases had a history of HIV-related toxoplasmosis and current virological and immunological control of HIV infection. Similar to neurocysticercosis, brain calcified toxoplasmosis may cause perilesional edema and symptoms in people living with HIV/AIDS.
病灶周围水肿，无论是否伴有神经症状，在钙化型神经囊尾蚴病病例中是一种特征明显的表现。既往尚无关于模仿神经囊尾蚴病这种表现的HIV相关钙化型弓形虫病的报道。我们报告了5例患者，其中4例有新发神经症状，这些患者表现出与病灶周围水肿相关的脑钙化。所有病例均有HIV相关弓形虫病病史且目前HIV感染的病毒学和免疫学控制良好。与神经囊尾蚴病相似，脑钙化型弓形虫病可能在HIV/AIDS患者中引起病灶周围水肿和症状。
