Department of Anesthesiology, West China Second University Hospital; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), Sichuan University, Chengdu, China.
BMC Pregnancy Childbirth. 2022 Apr 28;22(1):369. doi: 10.1186/s12884-022-04701-3.
For a healthy parturient, a cardiopulmonary collapse that suddenly occurs shortly after an uneventful caesarean section is a relatively rare event and presents a significant challenge for the anesthesia provider.
Amniotic fluid embolism (AFE) is characterized by acute and rapid collapse and is well known to the obstetric team. Our patient experienced sudden cardiovascular collapse, severe respiratory difficulty and hypoxia, in the absence of other explanations for these findings at the time, and thus AFE was immediately become the focus of the consideration. However, there is no quick, standard laboratory test for AFE, therefore the diagnosis is one of exclusion based on presenting symptoms and clinical course. After given symptomatic treatment, the patient made an uneventful initial recovery in a short period and developed a rash. We recognized that the postpartum shock was associated with delayed anaphylaxis of antibiotics.
These observations have implications for understanding whenever administering drugs in surgery, which may affect the anesthesiologist's judgment regarding the complications of anesthesia. Even though serious complications of common perioperative drugs may rarely occur, anesthesia providers should be aware of the consideration. Early recognition and effective treatment are more important than prompt diagnosis.
对于健康的产妇,在剖宫产术后不久突然发生心肺骤停是相对罕见的事件,对麻醉师来说是一个重大挑战。
羊水栓塞(AFE)的特征是急性和迅速的衰竭,产科团队对此非常熟悉。我们的患者在没有其他解释这些发现的情况下突然出现心血管衰竭、严重呼吸困难和缺氧,因此 AFE 立即成为关注的焦点。然而,目前没有针对 AFE 的快速、标准的实验室检测方法,因此诊断是基于临床表现和临床过程的排除性诊断。在给予对症治疗后,患者在短时间内顺利初步恢复,并出现皮疹。我们认识到产后休克与抗生素迟发性过敏反应有关。
这些观察结果对于理解在手术中给药时可能会影响麻醉师对麻醉并发症的判断具有重要意义。尽管常见围手术期药物的严重并发症可能很少发生,但麻醉师应该注意这一点。早期识别和有效治疗比及时诊断更为重要。