Codru Ioana Roxana, Codru Marian Valeriu, Vintilă Bogdan Ioan, Gherman Ioana, Popescu Dragoș
Faculty of Medicine, Lucian Blaga University of Sibiu, Romania.
Anesthesia and Intensive Care Clinic, Sibiu Emergency County Hospital, Romania.
J Crit Care Med (Targu Mures). 2024 Jan 30;10(1):103-107. doi: 10.2478/jccm-2024-0001. eCollection 2024 Jan.
Sudden respiratory and circulatory collapse during or immediately after delivery, vaginal or surgical, can have many causes that can lead to poor maternal outcomes. A pregnancy-induced amniotic fluid embolism and anaphylaxis are two distinct medical conditions that appear similar clinically but have very different underlying mechanisms and treatment approaches. Amniotic fluid embolism is a rare but life-threatening obstetric emergency that leads to a systemic inflammatory response that can be easily confounded with an anaphylactic reaction. We report the case of a patient with no comorbidities or allergies before the current pregnancy that was proposed for delivery by C-Section under spinal anesthesia. After delivery of the placenta and administering the test dose of antibiotic, the patient developed sudden circulatory collapse, altered neurological status, and critical respiratory distress. At that point, the two presumed diagnoses were amniotic fluid embolism and anaphylaxis. Concurrently with the diagnostic pathway, supportive measures (intubation, mechanical ventilation, hemodynamic support) were taken. The clinical evolution was favorable, and after day three, the patient was discharged from the hospital. Our case highlights the significance of promptly distinguishing between anaphylaxis and amniotic fluid embolism to facilitate the timely management of the critical situation.
在阴道分娩或剖宫产手术期间或之后立即出现的呼吸和循环系统突然衰竭,可能有多种原因,会导致不良的孕产妇结局。妊娠诱发的羊水栓塞和过敏反应是两种不同的病症,临床上看似相似,但潜在机制和治疗方法却大不相同。羊水栓塞是一种罕见但危及生命的产科急症,会引发全身炎症反应,很容易与过敏反应混淆。我们报告了一例患者,该患者在本次妊娠前无合并症或过敏史,拟在脊髓麻醉下进行剖宫产分娩。在胎盘娩出并给予抗生素试验剂量后,患者突然出现循环衰竭、神经状态改变和严重呼吸窘迫。此时,两种推测的诊断为羊水栓塞和过敏反应。在进行诊断的同时,采取了支持措施(插管、机械通气、血流动力学支持)。临床进展良好,三天后患者出院。我们的病例强调了迅速区分过敏反应和羊水栓塞对于及时处理危急情况的重要性。