School of Social Work, University of Michigan, Ann Arbor, MI, USA.
School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Asia Pac J Public Health. 2022 Jul;34(5):516-523. doi: 10.1177/10105395221095331. Epub 2022 Apr 29.
We examined whether baseline depression is associated with myocardial infarction (MI) within a 2-year period among middle-age and older adults in China and whether the association varies by sociodemographic characteristics. Two-year longitudinal data from a nationally representative sample of people aged 45+ years in China were analyzed (N = 15 226). MI within the 2-year period was coded dichotomously. Baseline depression, assessed by the 10-item Center for Epidemiological Studies Depression scale, was used as a dichotomous and a continuous variable. After adjusting for medical conditions, lifestyle, and sociodemographic characteristics, the odds of having an MI within the 2-year period were 46% greater for respondents with clinically significant depression at baseline than those without. There was a dose-response relationship between symptom severity and the probability of having an MI. The association did not vary by sociodemographic characteristics. Findings suggested that depression screening and treatment may reduce MI cases in China and beyond.
我们研究了在中国，中年及以上人群的基线抑郁是否与 2 年内的心肌梗死（MI）相关，以及这种相关性是否因社会人口特征而异。对来自中国年龄在 45 岁及以上的具有全国代表性的人群的 2 年纵向数据进行了分析（N=15226）。在 2 年内发生 MI 被编码为二分类变量。基线抑郁采用 10 项流行病学研究抑郁量表进行评估，作为二分类和连续变量。在调整医疗条件、生活方式和社会人口特征后，与没有抑郁的人相比，基线时存在临床显著抑郁的受访者在 2 年内发生 MI 的可能性要高出 46%。症状严重程度与发生 MI 的概率之间存在剂量-反应关系。这种相关性不受社会人口特征的影响。研究结果表明，在中国乃至全球，抑郁筛查和治疗可能会减少 MI 病例。
