Pereira João Pedro, Leitão Cátia, Alves Adriana, Jordão Sofia, Soares José
Gastrenterology, Hospital Pedro Hispano, Portugal.
Gastroenterology, Hospital Pedro Hispano.
Rev Esp Enferm Dig. 2022 Nov;114(11):681-682. doi: 10.17235/reed.2022.8875/2022.
A 40-year-old male with history of HIV infection was admitted to the hospital with a one-month history of productive cough, vespertine fever, night sweats, loss of appetite and unintentional 10-Kg weight loss. Physical exam was remarkable for cachexia. Blood tests revealed a CD4+ T lymphocyte count of 23 cells/mm3 and HIV viral load of 837,678 copies/ml. Bacilloscopies were positive. Chest computed thomography (CT) showed multiple mediastinal lymph nodes, signs of esophagomediastinal fistula, pericardial effusion and multiple micronodular pulmonary opacities. Endoscopy (EGD) revealed a 10 mm deep ulcer-like lesion in the middle esophagus with pus overflow, but no bubbles were seen. The diagnosis of stage C3 HIV infection with disseminated tuberculosis was made and the patient underwent standard antituberculosis (RIPE) and antiretroviral therapy. Given the mediastinitis risk a percutaneous endoscopic gastrostomy (PEG) tube was placed for nutritional purposes.
一名40岁有HIV感染史的男性因持续一个月的咳痰、傍晚发热、盗汗、食欲不振及非刻意减重10公斤入院。体格检查显示明显消瘦。血液检查显示CD4+ T淋巴细胞计数为23个/立方毫米,HIV病毒载量为837,678拷贝/毫升。涂片检查呈阳性。胸部计算机断层扫描(CT)显示多个纵隔淋巴结、食管纵隔瘘迹象、心包积液及多个微小结节状肺混浊。内镜检查(EGD)显示食管中段有一个10毫米深的溃疡样病变,有脓液溢出,但未见气泡。诊断为C3期HIV感染合并播散性结核病,患者接受了标准抗结核(RIPE)和抗逆转录病毒治疗。鉴于有纵隔炎风险,放置了经皮内镜下胃造口术(PEG)管用于营养支持。