Department of Internal Medicine, Talaghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Clinical Research Department Center, Imam Reza Hospital, Kermanshah University of Medical Science, Kermanshah, Iran.
Asian Pac J Cancer Prev. 2022 Apr 1;23(4):1263-1270. doi: 10.31557/APJCP.2022.23.4.1263.
According to the instructions of Iran's National Corona Response Committee in the Iranian Ministry of Health and Medical Education, patients undergoing treatments for their cancer are prioritized in Covid-19 vaccination. The present study was therefore conducted to investigate the toxicity and acute side-effects of a Covid-19 vaccine in cancer patients presenting to Medical Oncology Clinic of Kermanshah University of Medical Science. After excluding the patients with active infection and the recently-infected ones with Covid-19, they underwent the vaccination. The patients with cell counts exceeding 3,000 received two doses of the vaccine with a 21-day interval and treatment of their underlying disease was postponed for 7 days. The side-effects were mild and tolerable and included fever (case 10), pain at the injection site (7), dizziness (7), body pain (6), abdominal pain (6), myalgia (6), headache (6), chills (3), shortness of breath (3), diarrhea (1), runny nose (1) and dryness of the throat (1). No significant toxicity was reported in the patients who were safely vaccinated under the supervision of the medical oncology clinic.
根据伊朗卫生部和医疗教育部国家新冠应对委员会的指示，正在接受癌症治疗的患者在新冠疫苗接种中被优先考虑。因此，本研究旨在调查在克尔曼沙阿医科大学医学肿瘤学诊所就诊的癌症患者中新冠疫苗的毒性和急性副作用。在排除活动性感染和最近感染新冠的患者后，为他们接种了疫苗。细胞计数超过 3000 的患者接受两剂疫苗，间隔 21 天，同时推迟 7 天治疗基础疾病。副作用轻微且可耐受，包括发热（10 例）、注射部位疼痛（7 例）、头晕（7 例）、全身疼痛（6 例）、腹痛（6 例）、肌痛（6 例）、头痛（6 例）、寒战（3 例）、呼吸急促（3 例）、腹泻（1 例）、流鼻涕（1 例）和喉咙干燥（1 例）。在医学肿瘤学诊所的监督下，这些患者安全接种疫苗，未报告明显毒性。
