Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany; Schoen Clinic Roseneck, Prien am Chiemsee, Germany.
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
J Psychosom Res. 2022 Jul;158:110924. doi: 10.1016/j.jpsychores.2022.110924. Epub 2022 Apr 20.
Weight suppression refers to the difference between an individual's current and highest body weight at their current height. Higher weight suppression has been found to predict weight gain in both non-clinical samples and patients with eating disorders. Few studies also have reported interactive effects between weight suppression and current body mass index when predicting weight gain.
In this retrospective study, we analyzed clinical records of inpatients with anorexia nervosa (N = 2191, 97% female) and tested whether weight suppression and body mass index at admission would interactively predict different weight trajectories during treatment.
Body weight increased non-linearly during treatment. Higher weight suppression predicted larger weight gain but the nature of this effect depended on body mass index at admission. In patients with a relatively low body weight at admission, those with high weight suppression started at a lower weight and showed a nearly linear and steeper weight gain than those with low weight suppression. In patients with a relatively high body weight at admission, those with high weight suppression started at a similar weight and showed a non-linear and larger weight gain than those with low weight suppression.
Findings further support that weight suppression is a robust predictor of weight gain in addition to-and in interaction with-current body weight. As weight suppression can easily be assessed at admission, it may help to anticipate treatment course and outcome in patients with anorexia nervosa.
体重抑制是指个体当前身高下的当前体重与最高体重之间的差异。较高的体重抑制已被发现可预测非临床样本和饮食失调患者的体重增加。一些研究还报告了体重抑制和当前体重指数在预测体重增加方面的交互作用。
在这项回顾性研究中，我们分析了厌食症住院患者的临床记录（N=2191，女性占 97%），并测试了入院时的体重抑制和体重指数是否会相互作用，预测治疗期间的不同体重轨迹。
体重在治疗过程中呈非线性增加。较高的体重抑制预示着更大的体重增加，但这种效应的性质取决于入院时的体重指数。在入院时体重相对较低的患者中，体重抑制较高的患者体重起点较低，体重增加呈近乎线性且更为陡峭；而体重抑制较低的患者体重增加则较为平缓。在入院时体重较高的患者中，体重抑制较高的患者体重起点相似，但体重增加呈非线性且更大。
这些发现进一步支持体重抑制是体重增加的一个强有力的预测指标，除了当前体重之外，还与当前体重相互作用。由于体重抑制可以在入院时轻松评估，因此它可能有助于预测厌食症患者的治疗过程和结果。
