Inoue H, Gushi K, Matsuura S, Sakata Y
Biochem Biophys Res Commun. 1987 Feb 27;143(1):323-8. doi: 10.1016/0006-291x(87)90668-1.
Advantage of cloning probe DNA fragment in phage M13 DNA was taken to provide a larger single stranded DNA as a hybridization probe. High level of direct enzyme labels was introduced via the M13 DNA moiety as well as probe DNA. A highly sensitive colorimetric detection of virus DNA and oncogene was developed.
