肝移植候选者中慢性肾脏病和严重肝肾损伤的肾脏分配问题。
Kidney Allocation Issues in Liver Transplantation Candidates with Chronic Kidney Disease and Severe Kidney Liver Injury.
机构信息
Transplant Surgery Fellowship, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 400 Community Drive, Manhasset, NY 11765, USA.
Transplant Surgery Fellowship, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 400 Community Drive, Manhasset, NY 11765, USA.
出版信息
Clin Liver Dis. 2022 May;26(2):283-289. doi: 10.1016/j.cld.2022.01.004. Epub 2022 Apr 1.
The number of liver transplant candidates with concomitant renal disease has been steadily rising since the implementation of MELD-based allocation in 2002. Consequently, the number of simultaneous liver-kidney (SLK) transplants being performed each year has also increased. However, the establishment of well-defined criteria for when to choose SLK over liver transplant alone has lagged behind. The lack of clear guidelines has worsened an already large shortage of transplantable kidneys. This article further explores the rationale for and outlines the implementation of the SLK allocation policy.
自 2002 年实施基于 MELD 的分配以来，伴有肾脏疾病的肝移植候选者数量一直在稳步上升。因此，每年进行的同时肝-肾（SLK）移植数量也有所增加。然而，制定明确的标准来确定何时选择 SLK 而不是单独进行肝移植的工作却一直滞后。缺乏明确的指导方针使本来就严重短缺的可移植肾脏情况更加恶化。本文进一步探讨了 SLK 分配政策的基本原理并概述了其实施情况。
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