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肝肾联合移植新器官分配系统及4-5期慢性肾脏病患者可获得的移植肾情况

New Organ Allocation System for Combined Liver-Kidney Transplants and the Availability of Kidneys for Transplant to Patients with Stage 4-5 CKD.

作者信息

Asch William S, Bia Margaret J

机构信息

Section of Nephrology, Department of Internal Medicine, Yale University, New Haven, Connecticut.

出版信息

Clin J Am Soc Nephrol. 2017 May 8;12(5):848-852. doi: 10.2215/CJN.08480816. Epub 2016 Dec 27.

Abstract

A new proposal has been created for establishing medical criteria for organ allocation in recipients receiving simultaneous liver-kidney transplants. In this article, we describe the new policy, elaborate on the points of greatest controversy, and offer a perspective on the policy going forward. Although we applaud the fact that simultaneous liver-kidney transplant activity will now be monitored and appreciate the creation of medical criteria for allocation in simultaneous liver-kidney transplants, we argue that some of the criteria proposed, especially those for allocating a kidney to a liver recipient with AKI, are too liberal. We call on the nephrology community to follow the consequences of this new policy and push for a re-examination of the longstanding policy of allocating kidneys to multiorgan transplant recipients before all other candidates. The charge to protect our system of equitable organ allocation is very challenging, but it is a challenge that we must embrace.

摘要

一项关于为接受肝肾联合移植的受者制定器官分配医学标准的新提议已经出台。在本文中,我们描述了这项新政策,详细阐述了最具争议的要点,并对该政策的未来发展提供了一个观点。尽管我们赞赏现在将对肝肾联合移植活动进行监测这一事实,也感谢为肝肾联合移植分配制定医学标准,但我们认为所提议的一些标准,尤其是将肾脏分配给急性肾损伤的肝移植受者的标准过于宽松。我们呼吁肾脏病学界关注这项新政策的后果,并推动重新审视长期以来在所有其他候选者之前将肾脏分配给多器官移植受者的政策。保护我们公平的器官分配系统这一任务极具挑战性,但这是我们必须接受的挑战。

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