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甲醇中毒病例的脑病变迟发出血转化。

Late hemorrhagic transformation of brain lesions in case with methanol intoxication.

机构信息

Giresun Training and Research Hospital, Neurology Department, Giresun, Turkey.

Giresun Training and Research Hospital, Department of Intensive Care, Turkey.

出版信息

Neuroradiol J. 2022 Oct;35(5):658-661. doi: 10.1177/19714009221096822. Epub 2022 Apr 29.

Abstract

Methanol intoxication can be occurred as accidental or suicidal ingestion or intentional ingestion through abuse. Formic acid is the primary toxic metabolite which causes high anion gap metabolic acidosis and end-organ damage in the human body. Here we presented a 46-year-old man who loss of consciousness on the 23rd day of hospitalization and his cranial computed tomography revealed bilateral subcortical hemorrhages. This case indicates us an example of late appearance of hemorrhagic transformation in methanol intoxication.

摘要

甲醇中毒可因意外或自杀性摄入或通过滥用而故意摄入导致。甲酸是主要的毒性代谢产物,会导致人体高阴离子间隙代谢性酸中毒和靶器官损伤。本文报道了 1 例 46 岁男性,在住院第 23 天出现意识丧失,头颅 CT 显示双侧皮质下出血。该病例提示我们甲醇中毒后迟发出血转化的一个例子。

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本文引用的文献

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Methanol poisoning and heparin: a dangerous couple?甲醇中毒与肝素:危险组合?
Am J Emerg Med. 2004 Nov;22(7):620-1. doi: 10.1016/j.ajem.2004.08.004.

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