Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St., #3001, Philadelphia, PA, 19104, USA.
Department of Psychological Science, University of California, Irvine, CA, USA.
Child Psychiatry Hum Dev. 2023 Dec;54(6):1624-1652. doi: 10.1007/s10578-022-01352-5. Epub 2022 Apr 29.
Extant literature suggests a possible relationship between childhood trauma exposure and the development and trajectory of obsessive-compulsive symptoms (OCS) and obsessive-compulsive disorder (OCD); however, this relationship is poorly understood. We conducted a systematic review that examined trauma exposure and OCS/OCD in youth. Primary inclusion criteria were English-language articles that addressed a sample with participants under 18 years of age. 46 articles met criteria for review, and were categorized into three groups of overlap: Post-traumatic Stress Disorder (PTSD) and OCS or OCD (n = 3), clearly defined Criterion A event trauma exposure and OCS or OCD (n = 30), and less well-defined potential trauma exposure and OCS or OCD (n = 13). There was mixed evidence linking trauma exposure and the development of OCS or OCD in youth. Major methodological limitations preclude formal conclusions. More research on co-occurring trauma exposure and OCD/OCS in youth is needed to advance research and improve treatment.
现有文献表明，儿童期创伤暴露与强迫症症状（OCS）和强迫症（OCD）的发展和轨迹之间可能存在关系；然而，这种关系尚未得到充分理解。我们进行了一项系统评价，研究了青少年时期的创伤暴露与 OCS/OCD。主要纳入标准是针对年龄在 18 岁以下的参与者样本的英文文章。有 46 篇文章符合审查标准，并分为三组重叠：创伤后应激障碍（PTSD）和 OCS 或 OCD（n=3）、明确界定的 A 类事件创伤暴露和 OCS 或 OCD（n=30）和定义不明确的潜在创伤暴露和 OCS 或 OCD（n=13）。创伤暴露与青少年 OCS 或 OCD 的发展之间的关联证据不一。主要的方法学限制排除了正式结论。需要更多关于青少年 OCD/OCS 共病创伤暴露的研究，以推进研究并改善治疗。
