Division of Neuroradiology, Department of Radiodiagnosis and Imaging, 29751Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Department of Neurosurgery, 29751Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Neuroradiol J. 2022 Dec;35(6):772-776. doi: 10.1177/19714009221096821. Epub 2022 Apr 29.
Interrupted aortic arch (IAA) is a very rare congenital anomaly carrying high neonatal mortality rate if left untreated. Rarer still, is its presentation in teenage or adulthood. This condition has been found to be complicated with cerebral aneurysms, which is a consequence of hemodynamic stress and hypertension secondary to arch interruption. Cerebral aneurysms can further complicate the clinical course and lead to poor clinical outcomes, especially if ruptured.
A 17-year-old female presented with ruptured basilar top aneurysm and was considered for endovascular coiling. Transfemoral access was chosen but the catheter could not be negotiated beyond proximal thoracic aorta. A computed tomographic angiography (CTA) of thorax and abdomen was performed, which showed isolated interruption of aortic arch. Subsequently, transradial route was used for coiling of the aneurysm.
To the best of our knowledge, the index case is one of the only seven cases of IAA with cerebral aneurysm that have been reported till date in medical literature. It also holds the unique distinction of being the first case of IAA with cerebral aneurysm treated by endovascular approach. Our case highlights the importance of transradial access in such pathological conditions.
主动脉弓中断(IAA)是一种非常罕见的先天性畸形,如果不治疗,新生儿死亡率很高。更为罕见的是,它在青少年或成年期出现。这种情况常并发颅内动脉瘤,这是由于弓中断导致的血流动力学压力和高血压所致。颅内动脉瘤会进一步使病情复杂化,并导致不良的临床结局,尤其是破裂时。
一名 17 岁女性因基底动脉顶端破裂性动脉瘤就诊,拟行血管内线圈栓塞术。选择经股动脉入路,但导管无法通过近段胸主动脉。进行了胸部和腹部的 CT 血管造影(CTA)检查,显示孤立性主动脉弓中断。随后,经桡动脉途径对动脉瘤进行了线圈栓塞。
据我们所知,该病例是目前医学文献中仅有的七例 IAA 合并颅内动脉瘤病例之一。它还具有独特的区别,是首例经血管内途径治疗的 IAA 合并颅内动脉瘤病例。我们的病例强调了在这种病理情况下经桡动脉入路的重要性。