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尼日利亚西北部卡杜纳州的银屑病:二十年经验

Psoriasis in Kaduna, North-West Nigeria: A twenty-year experience.

作者信息

Yahya Husain

机构信息

Department of Internal Medicine, Barau Dikko Teaching Hospital, Kaduna State University, Kaduna, Nigeria.

出版信息

Niger Postgrad Med J. 2022 Apr-Jun;29(2):155-160. doi: 10.4103/npmj.npmj_15_22.

DOI:10.4103/npmj.npmj_15_22
PMID:35488585
Abstract

BACKGROUND

Psoriasis is a chronic inflammatory skin disease which may be associated with joint, cardiovascular, metabolic or psychiatric disease. Countries in North America, Northern Europe and Australia have the highest burden of disease while those in Asia, South America and Africa, the lowest. We report our experience of psoriasis in Kaduna, Nigeria, over 20 years and compare this with previous reports in the same area and in other parts of Nigeria and Africa.

OBJECTIVE

To report the relative incidence, clinical presentation, severity and associations of psoriasis seen over 20 years.

METHODS

A retrospective review of records of patients with psoriasis seen at two outpatient dermatology clinics in Kaduna, North-West Nigeria, over 20 years.

RESULTS

Diagnosis of psoriasis was made in 218 of 39,037 (0.6%) patients with new skin disease: Mean age 35.2 years, range (6 months to 80 years), 60% <40 years, males constituted 64.2%. Mean age of onset was 30.5 years with a quarter developing psoriasis before age 20 and 71.4% before 40 years. Psoriasis presented earlier in females than males (mean age of onset 27.6 vs. 32.2 years, P= 0.052) but was less severe. Psoriasis types were: Plaque 88.1%, guttate 6%, erythrodermic 4.6% and sebopsoriasis 0.9%. Only four patients had joint disease and other associations were infrequent. Overall, 80.3% had mild psoriasis and 13.2% had a family history.

CONCLUSION

Psoriasis remains a rare and mild disease in Kaduna and is infrequently associated with joint and other systemic disease but similar in other respects to the condition elsewhere.

摘要

背景

银屑病是一种慢性炎症性皮肤病,可能与关节、心血管、代谢或精神疾病相关。北美、北欧和澳大利亚的国家疾病负担最高,而亚洲、南美和非洲的国家负担最低。我们报告了在尼日利亚卡杜纳20多年来银屑病的诊治经验,并将其与该地区及尼日利亚和非洲其他地区以前的报告进行比较。

目的

报告20年来银屑病的相对发病率、临床表现、严重程度及相关性。

方法

对尼日利亚西北部卡杜纳两家门诊皮肤科诊所20年来诊治的银屑病患者记录进行回顾性分析。

结果

39037例新发皮肤病患者中有218例(0.6%)被诊断为银屑病:平均年龄35.2岁,范围(6个月至80岁),60%小于40岁,男性占64.2%。平均发病年龄为30.5岁,四分之一的患者在20岁前发病,71.4%在40岁前发病。女性银屑病发病早于男性(平均发病年龄27.6岁对32.2岁,P=0.052),但病情较轻。银屑病类型为:斑块状88.1%,点滴状6%,红皮病型4.6%,脂溢性皮炎型0.9%。只有4例患者有关节疾病,其他相关性疾病较少见。总体而言,80.3%的患者为轻度银屑病,13.2%有家族史。

结论

银屑病在卡杜纳仍然是一种罕见的轻度疾病,很少与关节及其他系统性疾病相关,但在其他方面与其他地区的情况相似。

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