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姑息治疗与有记录自杀:高死亡风险退伍军人之间的关联。

Palliative Care and Documented Suicide: Association Among Veterans With High Mortality Risk.

机构信息

Veteran Experience Center (A.K.L., J.G.C., H.G., D.K., D.S., J.M.T.,), Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA; Center for Health Equity Research and Promotion (A.K.L., M.E.), Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA; University of Pennsylvania School of Nursing (A.K.L., M.E.), Philadelphia, Pennsylvania, USA.

Mental Illness Research, Education, and Clinical Center of the Veterans Integrated Service Network 4 (G.K.K.), Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA.

出版信息

J Pain Symptom Manage. 2022 Aug;64(2):e63-e69. doi: 10.1016/j.jpainsymman.2022.04.179. Epub 2022 Apr 28.

Abstract

CONTEXT

Palliative care consultations (PCCs) are associated with reduced physical and psychological symptoms that are related to suicide risk. Little is known, however, about the association between PCCs and death from suicide among patients at high risk of short-term mortality.

OBJECTIVE

To examine the association between the number of PCCs and documentation of suicide in a cohort of Veterans at high risk of short-term mortality, before and after accounting for Veterans' sociodemographic characteristics and clinical conditions.

METHODS

An observational cohort study was conducted using linked Veterans Affairs clinical and administrative databases for 580,620 decedents with high risk of one-year mortality. Logistic regression models were used to examine the association between number of PCCs and documentation of suicide.

RESULTS

Higher percentages of Veterans who died by suicide were diagnosed with chronic pulmonary disease as well as mental health/substance use conditions compared with Veterans who died from other causes. In adjusted models, one PCC in the 90 days prior to death was significantly associated with a 71% decrease in the odds of suicide (OR = 0.29, 95% CI = 0.23-0.37, P < 0.001) and two or more PCCs were associated with a 78% decrease (OR = 0.22, 95% CI = 0.15-0.33, P < 0.001). Associated "number needed to be exposed" estimates suggest that 421 Veterans in this population would need to receive at least one PCC to prevent one suicide.

CONCLUSION

While acknowledging the importance of specialized mental health care in reducing suicide among high-risk patients, interventions delivered in the context of PCCs may also play a role.

摘要

背景

姑息治疗咨询(Palliative care consultations,PCCs)与降低与自杀风险相关的身体和心理症状有关。然而,对于 PCCs 与短期死亡率高的患者自杀死亡之间的关联知之甚少。

目的

在考虑退伍军人的社会人口统计学特征和临床状况后,研究高短期死亡率风险退伍军人队列中 PCC 次数与自杀记录之间的关联。

方法

使用退伍军人事务部临床和管理数据库的链接对 580620 名高一年死亡率风险的死者进行了一项观察性队列研究。使用逻辑回归模型检查 PCC 次数与自杀记录之间的关联。

结果

与因其他原因死亡的退伍军人相比,自杀退伍军人中有更高比例的人被诊断患有慢性肺部疾病以及心理健康/物质使用障碍。在调整后的模型中,死亡前 90 天内进行的一次 PCC 与自杀风险降低 71%显著相关(OR=0.29,95%CI=0.23-0.37,P<0.001),而进行两次或更多次 PCC 则与自杀风险降低 78%相关(OR=0.22,95%CI=0.15-0.33,P<0.001)。相关的“需要暴露的人数”估计表明,该人群中需要有 421 名退伍军人接受至少一次 PCC 以预防一次自杀。

结论

虽然承认专门的心理健康护理在降低高危患者自杀率方面的重要性,但在 PCC 背景下提供的干预措施也可能发挥作用。

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