Saffitz J E, Schwartz C J
Cardiol Clin. 1987 Feb;5(1):21-30.
Autopsy and clinical studies indicate that coronary thrombosis plays a key role in the development of acute transmural myocardial infarction and possibly in unstable angina and sudden cardiac death. The pathogenesis of coronary thrombosis is complex. It involves the dynamic interplay among the atherosclerotic arterial wall, vasomotor influences, cellular and humoral mediators, and the blood coagulation pathways.
尸检和临床研究表明，冠状动脉血栓形成在急性透壁性心肌梗死的发生发展中起关键作用，可能在不稳定型心绞痛和心源性猝死中也起关键作用。冠状动脉血栓形成的发病机制很复杂。它涉及动脉粥样硬化血管壁、血管舒缩影响、细胞和体液介质以及凝血途径之间的动态相互作用。
