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假说:缺血性斑块坏死是不稳定型心绞痛/急性心肌梗死的起始因素吗?

Hypothesis: ischaemic plaque necrosis as the initiator of unstable angina/acute myocardial infarction?

作者信息

Boyd G W

机构信息

Department of Medicine, University of Tasmania, Hobart, Australia.

出版信息

Clin Exp Pharmacol Physiol. 1990 Mar;17(3):215-8. doi: 10.1111/j.1440-1681.1990.tb01309.x.

Abstract
  1. Coronary atherosclerotic plaque complications are important in precipitating acute coronary events such as unstable angina and myocardial infarction. 2. The hypothesis is put forward that plaque complications are initiated by increases in local coronary artery tone sufficient to cut off the vasa vasorum blood supply to the plaque and result in its ischaemic necrosis.
摘要
  1. 冠状动脉粥样硬化斑块并发症在引发急性冠脉事件如不稳定型心绞痛和心肌梗死方面很重要。2. 有人提出这样的假说,即斑块并发症是由局部冠状动脉张力增加引发的,这种增加足以切断滋养血管对斑块的血液供应,导致其缺血性坏死。

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