Low-affinity CAR T cells exhibit reduced trogocytosis, preventing rapid antigen loss, and increasing CAR T cell expansion.
作者信息
Olson Michael L, Mause Erica R Vander, Radhakrishnan Sabarinath V, Brody Joshua D, Rapoport Aaron P, Welm Alana L, Atanackovic Djordje, Luetkens Tim
机构信息
Department of Pathology, University of Utah, Salt Lake City, UT, USA.
Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
出版信息
Leukemia. 2022 Jul;36(7):1943-1946. doi: 10.1038/s41375-022-01585-2. Epub 2022 Apr 30.
Abstract
摘要
Zotero 插件