Sorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie Et de Santé Publique (IPLESP), Paris, France.
Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, Paris, France.
BMC Public Health. 2022 Apr 30;22(1):865. doi: 10.1186/s12889-022-13296-5.
Screen media use in early childhood has largely increased in recent years, even more so during the COVID-19 epidemic, and there is much discussion regarding its influence on neurodevelopment, including Autism Spectrum Disorder (ASD).
We examined the relationship between use of TV, computer, tablet and smartphone at age 2 years and risk of ASD assessed in telephone-based questionnaires among 12,950 children participating in the nationally representative ELFE ('Etude Longitudinale Française sur les Enfants') birth cohort study in France.
In inverse-probability weighted (IPW) multinomial regression analyses, children's weekly or daily screen media use was associated with an increased likelihood of an intermediate risk of ASD (IPW-controlled OR for weekly use:1.07, 95% CI 1.02-1.12; IPW-controlled OR for daily use:1.05, 95% CI 1.02-1.08) but inversely associated with a high risk (IPW-controlled OR for weekly use: 0.60, 95% CI 0.50-0.73; IPW-controlled OR for daily use: 0.75, 95% CI 0.62-0.91), as ascertained by the M-CHAT. This was confirmed when studying TV as well as computer/tablet exposure separately.
Overall, our nationally-representative study conducted among a large sample of 2-year-old children, indicates a complex relationship between screen exposure and ASD risk.
近年来，儿童在幼年时期使用屏幕媒体的情况大幅增加，尤其是在 COVID-19 疫情期间，人们对其对神经发育的影响，包括自闭症谱系障碍（ASD），展开了大量讨论。
我们研究了在法国全国代表性的 ELFE（“法国儿童纵向研究”）出生队列研究中，12950 名儿童在 2 岁时使用电视、电脑、平板电脑和智能手机的情况与通过电话进行的 ASD 风险评估之间的关系。
在逆概率加权（IPW）多项回归分析中，儿童每周或每天使用屏幕媒体与 ASD 中度风险增加相关（每周使用的 IPW 校正比值比：1.07，95%CI 1.02-1.12；每日使用的 IPW 校正比值比：1.05，95%CI 1.02-1.08），但与高风险呈负相关（每周使用的 IPW 校正比值比：0.60，95%CI 0.50-0.73；每日使用的 IPW 校正比值比：0.75，95%CI 0.62-0.91），这是通过 M-CHAT 确定的。当分别研究电视和计算机/平板电脑暴露情况时，也得到了证实。
总的来说，我们在一个由大量 2 岁儿童组成的代表性样本中进行的全国性研究表明，屏幕暴露与 ASD 风险之间存在复杂的关系。
