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经单或双节段融合术治疗退行性病变患者的矢状面平衡:术后 6 个月的多中心放射学评估。

The Impact of Surgical Approach on Sagittal Plane Alignment in Patients Undergoing One- or Two- Level Fusions for Degenerative Pathology: A Multicenter Radiographic Evaluation 6 Months Following Surgery.

机构信息

Center for Neurosciences and Spine, Department of Neurosurgery, Virginia Mason Franciscan Health, Seattle, Washington, USA.

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

World Neurosurg. 2022 Aug;164:e311-e317. doi: 10.1016/j.wneu.2022.04.093. Epub 2022 Apr 28.

Abstract

OBJECTIVE

Interbody fusion procedures, including transforaminal (TLIF), posterior (PLIF), anterior (ALIF), and lateral (LLIF), effectively treat lumbar degenerative pathology and provide spinopelvic balance. The objective of this study is to compare changes in spinopelvic parameters 6 months following 1-2 level TLIF, PLIF, ALIF, and LLIF.

METHODS

This retrospective study included 18 centers across the United States. Patients were included in the study if they underwent a 1- or 2-level primary lumbar fusion for degenerative pathology. Preoperative and 6-month postoperative lumbar anteroposterior and lateral lumbar plain radiograph measurements included: pelvic incidence, pelvic tilt, lumbar lordosis from L1-S1, and segmental lordosis of each segment between L1 and S1.

RESULTS

A total of 474 patients met inclusion criteria, with 632 levels that underwent fusion. Of these, 181 patients underwent an ALIF/LLIF on 381 levels, and 188 underwent a TLIF/PLIF on 252 levels. ALIF/LLIF procedures resulted in significantly more segmental lordosis (P < 0.001) and global lumbar lordotic alignment change (P < 0.01) compared with TLIF/PLIF procedures. Whether patients' alignment was preserved versus worsened was not significantly predicted by type of procedure. Similarly, whether patients' alignment was restored versus not corrected was not significantly predicted by procedure.

CONCLUSIONS

In this large-scale multicenter study of lumbar fusion patients presenting with degenerative lumbar pathology, anteriorly placed grafts (ALIF/LLIF) led to a greater likelihood of patients being preserved rather than worsened in their spinopelvic mismatch. Posteriorly placed TLIF or PLIF grafts tended to worsen lordosis both segmentally and globally, yet even the anterior grafts only modestly improved those 2 same measurements.

摘要

目的

经椎间孔(TLIF)、后路(PLIF)、前路(ALIF)和侧方(LLIF)融合术等节段融合术可有效治疗腰椎退行性病变,并提供脊柱骨盆平衡。本研究旨在比较 1-2 个节段 TLIF、PLIF、ALIF 和 LLIF 术后 6 个月脊柱骨盆参数的变化。

方法

这是一项在美国 18 个中心进行的回顾性研究。纳入标准为:因退行性病变行 1-2 个节段原发性腰椎融合术的患者。术前及术后 6 个月行腰椎前后位及侧位平片测量,包括骨盆入射角、骨盆倾斜角、L1-S1 腰椎前凸、L1-S1 各节段的节段前凸。

结果

共纳入 474 例患者,632 个节段接受融合。其中,181 例患者接受 ALIF/LLIF 治疗,共 381 个节段;188 例患者接受 TLIF/PLIF 治疗,共 252 个节段。与 TLIF/PLIF 相比,ALIF/LLIF 可显著增加节段前凸(P<0.001)和整体腰椎前凸变化(P<0.01)。无论患者的脊柱排列是保持还是恶化,与手术类型均无显著相关性。同样,无论患者的脊柱排列是恢复还是未纠正,也与手术类型无显著相关性。

结论

在这项针对退行性腰椎病变患者的大型多中心腰椎融合研究中,前位植骨(ALIF/LLIF)更有可能保持患者的脊柱骨盆不匹配,而不是恶化。后位 TLIF 或 PLIF 植骨更倾向于导致节段和整体前凸恶化,即使是前位植骨也只能适度改善这两个测量值。

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