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休克指数、舒张期休克指数、年龄休克指数和改良休克指数在 COVID-19 肺炎中的预后性能。

Prognostic Performance of Shock Index, Diastolic Shock Index, Age Shock Index, and Modified Shock Index in COVID-19 Pneumonia.

机构信息

Department of Emergency Medicine, Antalya Training and Research Hospital; University of Health Sciences, Antalya/Turkey.

Department of Emergency Medicine, Bakirkoy Doctor Sadi Konuk Training and Research Hospital; University of Health Sciences, Istanbul, Turkey.

出版信息

Disaster Med Public Health Prep. 2022 May 2;17:e189. doi: 10.1017/dmp.2022.110.

Abstract

OBJECTIVE

We aimed to compare the prognostic accuracy of shock indexes in terms of mortality in patients hospitalized with coronavirus disease 2019 (COVID-19) pneumonia.

METHODS

Hospitalized patients whose COVID-19 reverse transcriptase-polymerase chain reaction (RT-PCR) test results were positive, had thoracic computed tomography (CT) scan performed, and had typical thoracic CT findings for COVID-19 were included in the study.

RESULTS

Eight hundred one patients were included in the study. Chronic obstructive pulmonary disease, congestive heart failure, chronic neurological diseases, chronic renal failure, and a history of malignancy were found to be chronic diseases that were significantly associated with mortality in patients with COVID-19 pneumonia. White blood cell, neutrophil, lymphocyte, C reactive protein, creatinine, sodium, aspartate aminotransferase, alanine aminotransferase, total bilirubin, high sensitive troponin, d-dimer, hemoglobin, and platelet had a statistically significant relationship with in-hospital mortality in patients with COVID-19 pneumonia. The area under the curve (AUC) values of shock index (SI), age shock index (aSI), diastolic shock index (dSI), and modified shock index (mSI) calculated to predict mortality were 0.772, 0.745, 0.737, 0.755, and Youden Index J (YJI) values were 0.523, 0.396, 0.436, 0.452, respectively.

CONCLUSIONS

The results of this study show that SI, dSI, mSI, and aSI are effective in predicting in-hospital mortality.

摘要

目的

比较休克指数在预测新冠肺炎(COVID-19)肺炎住院患者死亡率方面的预后准确性。

方法

纳入 COVID-19 逆转录-聚合酶链反应(RT-PCR)检测结果阳性、进行过胸部计算机断层扫描(CT)检查且具有 COVID-19 典型胸部 CT 表现的住院患者。

结果

本研究共纳入 801 例患者。慢性阻塞性肺疾病、充血性心力衰竭、慢性神经系统疾病、慢性肾衰竭和恶性肿瘤病史被认为是 COVID-19 肺炎患者死亡的显著相关慢性疾病。白细胞、中性粒细胞、淋巴细胞、C 反应蛋白、肌酐、钠、天门冬氨酸氨基转移酶、丙氨酸氨基转移酶、总胆红素、高敏肌钙蛋白、D-二聚体、血红蛋白和血小板与 COVID-19 肺炎住院患者的院内死亡率有统计学显著关系。计算预测死亡率的休克指数(SI)、年龄休克指数(aSI)、舒张期休克指数(dSI)和改良休克指数(mSI)的曲线下面积(AUC)值分别为 0.772、0.745、0.737、0.755,约登指数 J(YJI)值分别为 0.523、0.396、0.436、0.452。

结论

本研究结果表明,SI、dSI、mSI 和 aSI 可有效预测住院患者的死亡率。

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