Wang Wen-Li, Jin Ren-Hua
Department of Material and Life Chemistry, Kanagawa University 3-27-1 Rokkakubashi Yokohama 221-8686 Japan
RSC Adv. 2020 Apr 1;10(22):13260-13266. doi: 10.1039/c9ra10704e. eCollection 2020 Mar 30.
In this work, we synthesized a new comb-like copolymer (c-iMP) possessing amphiphilic diblock side chains consisting of poly(methyloxazoline) (PMOZ) and poly(phenyloxazoline) (PPOZ) reversible addition-fragmentation chain-transfer (RAFT) polymerization of -choloromethylstyene (CMS) and cationic ring-opening polymerization (CROP) of 2-methyl-2-oxazoline (MOZ) and 2-phenyl-2-oxazoline (POZ). Then, by performing selective hydrolysis of the hydrophilic PMOZ block, the PMOZ block was transformed into PEI (polyethylenimine) from which comb-like copolymers (c-iEP) possessing two blocks of PEI (E) and PPOZ (P) were produced. The comb-copolymers c-iEP showed unique self-assembling behavior in water to give an unusual polymersome covered by a loop-cluster polyamine corona. The polymersome showed extreme toughness and stability without collapse and fusion even at dry conditions and could be transformed into capsules. This is the first example of polymesome without free-ends on the vesicle wall which could include Ag ions inside and could deposit silica around the wall to form hybrid hollow spheres.
在这项工作中，我们通过对氯甲基苯乙烯（CMS）进行可逆加成-断裂链转移（RAFT）聚合以及对2-甲基-2-恶唑啉（MOZ）和2-苯基-2-恶唑啉（POZ）进行阳离子开环聚合（CROP），合成了一种新型梳状共聚物（c-iMP），其具有由聚（甲基恶唑啉）（PMOZ）和聚（苯基恶唑啉）（PPOZ）组成的两亲性二嵌段侧链。然后，通过对亲水性PMOZ嵌段进行选择性水解，将PMOZ嵌段转化为聚乙烯亚胺（PEI），从而制备出具有PEI（E）和PPOZ（P）两个嵌段的梳状共聚物（c-iEP）。梳状共聚物c-iEP在水中表现出独特的自组装行为，形成一种由环状簇聚胺冠层覆盖的异常聚合物囊泡。该聚合物囊泡表现出极高的韧性和稳定性，即使在干燥条件下也不会塌陷和融合，并且可以转化为胶囊。这是囊泡壁上没有自由端的聚合物囊泡的首个实例，其能够在内部包含银离子，并能在壁周围沉积二氧化硅以形成杂化空心球体。
