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佩罗尼氏病的多处斑块切开术,伴或不伴移植术。

Multiple plaque incisions with or without grafting for Peyronie's disease.

作者信息

Hegarty Paul K, O Sullivan Daniel, Hegarty Penelope A, Zafirakis Helen

机构信息

Total Urology Affidea Diagnostics Cork Ireland.

Department of Medicine University College Cork Cork Ireland.

出版信息

BJUI Compass. 2022 Jan 12;3(3):220-225. doi: 10.1002/bco2.130. eCollection 2022 May.

DOI:10.1002/bco2.130
PMID:35492223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9045568/
Abstract

OBJECTIVES

To assess novel surgical techniques in management of Peyronie's disease.

SUBJECTS

Forty-three men underwent corrective surgery using either partial plaque incision and nongraft (PPING) or multiple plaque incisions and graft (MPIG). The technique used was determined intra-operatively. Patients were assessed at baseline and follow-up based on Peyronie's disease questionnaire patient-reported outcome measure (PDQ-PROM) and erectile function.

RESULTS

The two groups were well matched in age and erectile function. At baseline MPIG group had greater deformity and poorer patient-reported outcome. Penile curvature improved from 67.9° to 10.5° in the PPING group and 77.9° to 7.1° with MPIG. PDQ-PROM improved from 29 to 13 in those who underwent PPING and 38.5 to 17.6 in those undergoing MPIG. Erectile function was preserved in both groups.

CONCLUSIONS

These novel surgeries are effective in restoring penile shape and length while preserving erectile function. This is reflected in improved patient-reported outcomes. These findings should be verified by multi-institutional study.

摘要

目的

评估治疗佩罗尼氏病的新型手术技术。

研究对象

43名男性接受了矫正手术,采用部分斑块切开术且不植入移植物(PPING)或多次斑块切开术并植入移植物(MPIG)。手术中确定所使用的技术。根据佩罗尼氏病问卷患者报告结局指标(PDQ-PROM)和勃起功能,在基线和随访时对患者进行评估。

结果

两组在年龄和勃起功能方面匹配良好。在基线时,MPIG组的畸形更严重,患者报告的结局更差。PPING组阴茎弯曲度从67.9°改善至10.5°,MPIG组从77.9°改善至7.1°。接受PPING的患者PDQ-PROM从29改善至13,接受MPIG的患者从38.5改善至17.6。两组的勃起功能均得以保留。

结论

这些新型手术在恢复阴茎形状和长度的同时保留勃起功能方面是有效的。这体现在患者报告结局的改善上。这些发现应通过多机构研究进行验证。

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