佩罗尼氏病非手术治疗的批判性分析。

A critical analysis of nonsurgical treatment of Peyronie's disease.

作者信息

Hauck Ekkehard W, Diemer Thorsten, Schmelz Hans U, Weidner Wolfgang

机构信息

Department of Urology and Pediatric Urology, University Clinic Giessen and Marburg, Justus Liebig University Giessen, Germany.

出版信息

Eur Urol. 2006 Jun;49(6):987-97. doi: 10.1016/j.eururo.2006.02.059. Epub 2006 Mar 20.

DOI:10.1016/j.eururo.2006.02.059

PMID:16698449

Abstract

OBJECTIVE

Because the efficacy of nonsurgical therapy of Peyronie's disease is controversial, this review analyses the current status of conservative therapy of Peyronie's disease.

METHOD

A systematic survey on results of studies published as original papers in peer-reviewed journals is provided.

RESULTS

Oral drug therapies include potassium para-aminobenzoate (Potaba), vitamin E, colchicine, tamoxifen, propoleum, acetyl-L-carnitine, and propionyl-L-carnitine. Verapamil, interferon-alpha2a and interferon-alpha2b, collagenase, cortisone, hyaluronidase, and superoxide dismutase are considered intralesional therapies that have had various degrees of success. Other treatments include local gels, iontophoresis, extracorporeal shock wave therapy, and radiation.

CONCLUSION

This review analyses the current status of the conservative therapy of Peyronie's disease, because the efficacy of the nonsurgical therapy is controversial.

摘要

目的

由于佩罗尼氏病非手术治疗的疗效存在争议，本综述分析了佩罗尼氏病保守治疗的现状。

方法

提供了对在同行评审期刊上发表的作为原始论文的研究结果的系统调查。

结果

口服药物治疗包括对氨基苯甲酸钾（Potaba）、维生素E、秋水仙碱、他莫昔芬、凡士林、乙酰左旋肉碱和丙酰左旋肉碱。维拉帕米、干扰素-α2a和干扰素-α2b、胶原酶、可的松、透明质酸酶和超氧化物歧化酶被认为是病灶内治疗，已取得不同程度的成功。其他治疗方法包括局部凝胶、离子电渗疗法、体外冲击波疗法和放射治疗。