Chen Ze-Xu, Zhao Zhen-Nan, Sun Yang, Jia Wan-Nan, Zheng Jia-Lei, Chen Jia-Hui, Chen Tian-Hui, Lan Li-Na, Jiang Yong-Xiang
Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
NHC Key Laboratory of Myopia, Fudan University, Shanghai, China.
Front Med (Lausanne). 2022 Apr 14;9:869539. doi: 10.3389/fmed.2022.869539. eCollection 2022.
Microspherophakia (MSP) is a rare ocular condition, the lens surgery of which is complicated by both insufficient zonules and undersized capsule.
This study included MSP eyes managed with phacoemulsification combined with supra-capsular and scleral-fixated intraocular lens implantation (SCSF-IOL) and made the comparison with those treated by transscleral-fixated modified capsular tension ring and in-the-bag intraocular lens implantation (MCTR-IOL).
A total of 20 MSP patients underwent SCSF-IOL, and 17 patients received MCTR-IOL. The postoperative best corrected visual acuity was significantly improved in both groups ( < 0.001), but no difference was found between the groups ( = 0.326). The IOL tilt was also comparable ( = 0.216). Prophylactic Nd:YAG laser posterior capsulotomy was performed 1 week to 1 month after the SCSF-IOL procedure. In the SCSF-IOL group, two eyes (10.00%) needed repeated laser treatment and one eye (5.00%) had a decentered capsule opening. Posterior capsule opacification was the most common complication (6, 35.29%) in the MCTR group. No IOL dislocation, secondary glaucoma, or retinal detachment was observed during follow-up.
SCSF-IOL is a viable option for managing MSP and is comparable with the MCTR-IOL. Nd:YAG laser posterior capsulotomy was necessary to prevent residual capsule complications after the SCSF-IOL procedure.
小球形晶状体(MSP)是一种罕见的眼部疾病,其晶状体手术因悬韧带不足和囊袋过小而变得复杂。
本研究纳入了采用超声乳化联合囊袋上巩膜固定人工晶状体植入术(SCSF-IOL)治疗的MSP患眼,并与经巩膜固定改良囊袋张力环及囊袋内人工晶状体植入术(MCTR-IOL)治疗的患眼进行比较。
共有20例MSP患者接受了SCSF-IOL,17例患者接受了MCTR-IOL。两组术后最佳矫正视力均显著提高(<0.001),但两组间无差异(=0.326)。人工晶状体倾斜度也相当(=0.216)。SCSF-IOL术后1周~1个月进行预防性Nd:YAG激光后囊切开术。在SCSF-IOL组,2只眼(10.00%)需要重复激光治疗,1只眼(5.00%)囊袋开口偏心。后囊混浊是MCTR组最常见的并发症(6只眼,35.29%)。随访期间未观察到人工晶状体脱位、继发性青光眼或视网膜脱离。
SCSF-IOL是治疗MSP的一种可行选择,与MCTR-IOL相当。SCSF-IOL术后进行Nd:YAG激光后囊切开术对于预防残留囊袋并发症是必要的。