From the Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
J Cataract Refract Surg. 2020 Dec;46(12):1674-1679. doi: 10.1097/j.jcrs.0000000000000334.
As a rare congenital disease, microspherophakia (MSP) is characterized by small and spherically shaped crystalline lenses. The common complications of MSP include secondary glaucoma and crystalline lens dislocation or subluxation. Patients with MSP often show high lenticular myopia. The special morphological characteristics and complex complications bring challenges to the treatment of patients with MSP. Although there are some studies on MSP, most are case reports. In this article, the morphological characteristics, complications, genetic diagnosis, and treatment of MSP were systematically reviewed, providing valuable insight into the clinical diagnosis and treatment of this disease.
作为一种罕见的先天性疾病,小角膜(MSP)的特征为晶状体小且呈球形。MSP 的常见并发症包括继发性青光眼和晶状体脱位或半脱位。MSP 患者通常表现为高度晶状体近视。特殊的形态特征和复杂的并发症给 MSP 患者的治疗带来了挑战。尽管对 MSP 有一些研究,但大多数都是病例报告。本文对 MSP 的形态特征、并发症、遗传诊断和治疗进行了系统回顾,为该病的临床诊断和治疗提供了有价值的见解。