Tekle Yared, Hiware Sanket, Shameem Ahammed, Atlaw Daniel
Department of Anatomy, School of Medicine, College of Medicine and Health Science, Dire Dawa University, Dire Dawa, Ethiopia.
Department of Anatomy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
SAGE Open Med. 2022 Apr 25;10:20503121221094451. doi: 10.1177/20503121221094451. eCollection 2022.
The objective of this study is to determine the effect of Catha edulis leaves on glycosylated haemoglobin and lipid profiles in healthy individuals in Dire Dawa, Ethiopia.
A cross-sectional study was conducted to evaluate the effect of khat leaves on the glycated haemoglobin and lipid profile in the Dire Dawa population. For the study, 100 male subjects (aged ⩾20-⩽40 years) were recruited and divided into two groups, each consisting of 50 subjects: the first group was khat chewing people while the other group was non-khat chewing individuals. Blood samples were collected and tested to evaluate the glycated haemoglobin and lipid profiles.
The mean glycated haemoglobin value of khat chewers was 5.33% and for non-chewers, it was 5.48%, respectively. Since value is less than the significance value, the -test supports the reduction in glycated haemoglobin values in khat chewers. The mean values of total cholesterol, and triglycerides in khat chewers are 175.2 and 172.92, and for non-chewers they are 168.7 and 164.56, respectively.
From this study, we concluded that Catha edulis leaves have a significant effect on glycosylated haemoglobin levels. Mean glycated haemoglobin values of long-term healthy khat chewers are comparatively less than healthy non-chewers. Long-term khat chewing increases total cholesterol levels and triglycerides levels but there is no significant effect on the high-density lipoprotein and low-density lipoprotein levels.
本研究的目的是确定恰特草叶对埃塞俄比亚迪雷达瓦健康个体糖化血红蛋白和血脂谱的影响。
进行了一项横断面研究，以评估卡特叶对迪雷达瓦人群糖化血红蛋白和血脂谱的影响。在该研究中，招募了100名男性受试者（年龄≥20至≤40岁）并分为两组，每组50名受试者：第一组为咀嚼恰特草者，另一组为不咀嚼恰特草者。采集血样并进行检测以评估糖化血红蛋白和血脂谱。
咀嚼恰特草者的平均糖化血红蛋白值为5.33%，不咀嚼者为5.48%。由于该值小于显著性值，t检验支持咀嚼恰特草者糖化血红蛋白值降低。咀嚼恰特草者的总胆固醇和甘油三酯平均值分别为175.2和172.92，不咀嚼者分别为168.7和164.56。
从本研究中，我们得出结论，恰特草叶对糖化血红蛋白水平有显著影响。长期健康咀嚼恰特草者的平均糖化血红蛋白值相对低于健康不咀嚼者。长期咀嚼恰特草会增加总胆固醇水平和甘油三酯水平，但对高密度脂蛋白和低密度脂蛋白水平没有显著影响。
