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佐匹克隆与三唑仑临床催眠效果的比较。

Comparison of the clinical hypnotic effects of zopiclone and triazolam.

作者信息

Autret E, Maillard F, Autret A

出版信息

Eur J Clin Pharmacol. 1987;31(5):621-3. doi: 10.1007/BF00606643.

DOI:10.1007/BF00606643
PMID:3549323
Abstract

In a double blind crossover therapeutic trial the hypnotic effect of Zopiclone 7.5 mg and Triazolam 0.5 mg given orally at bedtime for 7 consecutive days have been compared. 5 of the items in Spiegel's questionnaire and 12 of the 18 items in Norris' visual analogue scale were significantly more improved by Zopiclone than by Triazolam. Both drugs caused few side-effects.

摘要

在一项双盲交叉治疗试验中,比较了连续7天每晚口服7.5毫克佐匹克隆和0.5毫克三唑仑的催眠效果。与三唑仑相比,佐匹克隆使施皮格尔问卷中的5项以及诺里斯视觉模拟量表18项中的12项有更显著的改善。两种药物的副作用都很少。

相似文献

1
Comparison of the clinical hypnotic effects of zopiclone and triazolam.佐匹克隆与三唑仑临床催眠效果的比较。
Eur J Clin Pharmacol. 1987;31(5):621-3. doi: 10.1007/BF00606643.
2
A comparison of the efficacy, safety and withdrawal effects of zopiclone and triazolam in the treatment of insomnia.佐匹克隆与三唑仑治疗失眠的疗效、安全性及撤药效应比较。
Int Clin Psychopharmacol. 1990 Apr;5 Suppl 2:29-37.
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Zopiclone and triazolam in insomnia associated with generalized anxiety disorder: a placebo-controlled evaluation of efficacy and daytime anxiety.
Int Clin Psychopharmacol. 1990 Jul;5(3):173-83. doi: 10.1097/00004850-199007000-00002.
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Zopiclone versus triazolam in insomniac geriatric patients: a specific increase in delta sleep with zopiclone.佐匹克隆与三唑仑治疗老年失眠患者的比较:佐匹克隆可使δ睡眠特异性增加。
Int Clin Psychopharmacol. 1990 Apr;5 Suppl 2:47-55.
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A comparative study of zopiclone and triazolam in patients with insomnia.佐匹克隆与三唑仑治疗失眠症患者的对比研究。
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Comparative clinical profiles of triazolam versus other shorter-acting hypnotics.三唑仑与其他短效催眠药的临床特征比较
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Efficacy and tolerance of zopiclone in insomniac geriatric patients.佐匹克隆对老年失眠患者的疗效及耐受性
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Comparative study of zopiclone and pentobarbitone as hypnotics.佐匹克隆与戊巴比妥作为催眠药的比较研究。
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Comparative study of zopiclone and pentobarbitone as hypnotics.佐匹克隆与戊巴比妥作为催眠药的比较研究。
Int Pharmacopsychiatry. 1982;17 Suppl 2:188-95.
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Zopiclone to geriatric patients. A parallel double-blind dose-response clinical trial of zopiclone as a hypnotic to geriatric patients - a study in a geriatric hospital.佐匹克隆用于老年患者。一项在老年医院进行的佐匹克隆作为催眠药用于老年患者的平行双盲剂量反应临床试验。
Int Pharmacopsychiatry. 1982;17 Suppl 2:173-8.

引用本文的文献

1
Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.《成人慢性失眠症药物治疗临床实践指南:美国睡眠医学会临床实践指南》
J Clin Sleep Med. 2017 Feb 15;13(2):307-349. doi: 10.5664/jcsm.6470.
2
Eszopiclone: its use in the treatment of insomnia.艾司佐匹克隆:在失眠治疗中的应用。
Neuropsychiatr Dis Treat. 2007 Aug;3(4):441-53.
3
A comparative assessment of the risks and benefits of zopiclone: a review of 15 years' clinical experience.

本文引用的文献

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Effectiveness of zopiclone as a preoperative hypnotic.
Pharmacology. 1983;27 Suppl 2:196-204. doi: 10.1159/000137927.
2
Polygraphical sleep recordings in insomniac patients under zopiclone or nitrazepam.唑吡坦或硝西泮治疗下失眠患者的多导睡眠记录
Pharmacology. 1983;27 Suppl 2:136-45. doi: 10.1159/000137920.
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5
Difference in action between oral triazolam and zopiclone.口服三唑仑与佐匹克隆的作用差异。
Eur J Clin Pharmacol. 1990;38(1):47-51. doi: 10.1007/BF00314802.
Efficacy and tolerance of zopiclone in insomniac geriatric patients.佐匹克隆对老年失眠患者的疗效及耐受性
Pharmacology. 1983;27 Suppl 2:179-87. doi: 10.1159/000137925.
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A comparative study of zopiclone and flunitrazepam in insomniacs seen by general practitioners.
Pharmacology. 1983;27 Suppl 2:165-72. doi: 10.1159/000137923.
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Effects of zopiclone as compared to flurazepam on sleep in women over 40 years of age.
Pharmacology. 1983;27 Suppl 2:146-55. doi: 10.1159/000137921.
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The action of sedatives on brain stem oculomotor systems in man.镇静剂对人类脑干动眼系统的作用。
Neuropharmacology. 1971 Mar;10(21):181-91. doi: 10.1016/0028-3908(71)90039-6.
8
Psychometric analysis of the Hypnotic Induction Profile.催眠诱导剖面图的心理测量分析。
Int J Clin Exp Hypn. 1976 Jul;24(3):300-15. doi: 10.1080/00207147608416210.