He Jiahua, Liu Jiawei, Liu Yangyang, Liyin Zhengxi, Wu Xiaoyi, Song Gang, Hou Yeyang, Wang Ruixi, Zhao Wenfeng, Sun Hui
College of Environmental Science and Engineering, Guangzhou University Guangzhou 510006 Guangdong China
School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University Xuzhou 221116 P. R. China
RSC Adv. 2021 Oct 6;11(52):32841-32851. doi: 10.1039/d1ra05084b. eCollection 2021 Oct 4.
In order to obtain high derivatization efficiency, the overuse of derivative agent 2,4-dinitrophenylhydrazine (2,4-DNPH) is necessary for carbonyl detection. But, the 2,4-DNPH residue will cause background interferences and limit the pre-concentration factor of the target analytes. In order to overcome the bottleneck problems, the magnetic molecularly imprinted polymer based solid-phase extraction (MMIPs-SPE) method was developed with 2,4-dinitroaniline (2,4-DNAN) as the dummy template. The characteristics and selectivity of the MMIPs were investigated. Under the optimized conditions, the enrichment of carbonyls-DNPH derivatives with simultaneous removal of the surplus 2,4-DNPH was achieved. By coupling with capillary electrophoresis (CE), a satisfactory analytical performance was obtained with the detection limit ranging from 1.2 to 8.7 μg L for 8 carbonyls. The MMIPs-SPE-CE method was applied successfully for the carbonyl assessment in stream water, tap water and bottled water. In addition, the migration of carbonyls in bottled drinking water was investigated under UV irradiation and heating.
为了获得高衍生化效率，在羰基检测中过度使用衍生剂2,4-二硝基苯肼（2,4-DNPH）是必要的。但是，2,4-DNPH残留会导致背景干扰并限制目标分析物的预浓缩因子。为了克服这些瓶颈问题，开发了以2,4-二硝基苯胺（2,4-DNAN）为虚拟模板的磁性分子印迹聚合物固相萃取（MMIPs-SPE）方法。研究了MMIPs的特性和选择性。在优化条件下，实现了羰基-DNPH衍生物的富集并同时去除了过量的2,4-DNPH。通过与毛细管电泳（CE）联用，对于8种羰基化合物获得了令人满意的分析性能，检测限在1.2至8.7μg/L之间。MMIPs-SPE-CE方法成功应用于溪水、自来水和瓶装水中羰基的评估。此外，还研究了瓶装饮用水中羰基在紫外线照射和加热条件下的迁移情况。
