Liu Xueping, Wu Ying, Zhang Minghui, Zhang Ke
State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, The Chinese Academy of Sciences Beijing 100190 China
School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences Beijing 100049 China.
RSC Adv. 2020 Feb 13;10(12):6794-6800. doi: 10.1039/c9ra09919k.
An efficient polymer dimerization method is developed on a self-accelerating double strain-promoted azide-alkyne cycloaddition (DSPAAC) click reaction. In this approach, varied polymer dimers can be efficiently prepared by coupling azide terminated polymer building blocks by -dibenzo-1,5-cyclooctadiene-3,7-diyne (DIBOD) small linkers. The distinct advantages of this method can be summarized as follows. First, the azide terminated polymer building blocks can be easily prepared with varied molecular topologies such as linear, star, and dendritic shapes. Second, the self-accelerating property of DSPAAC coupling reaction allows the method to efficiently prepare pure polymer dimers in the presence of excess molar amounts of DIBOD small linkers to azide-terminated polymer building blocks. Third, the click property of DSPAAC coupling reaction facilitates the dimerization reaction with a very mild ambient reaction condition. As a result, this method provides a powerful tool to fabricate topological polymers with a symmetrical molecular structure such as block, star, and dendritic polymers.
一种高效的聚合物二聚化方法是基于自加速双应变促进的叠氮化物-炔烃环加成（DSPAAC）点击反应开发的。在这种方法中，通过用 -二苯并-1,5-环辛二烯-3,7-二炔（DIBOD）小连接体偶联叠氮端基聚合物构建块，可以高效地制备各种聚合物二聚体。该方法的显著优点可总结如下。首先，叠氮端基聚合物构建块可以很容易地制备成具有各种分子拓扑结构，如线性、星形和树枝状形状。其次，DSPAAC偶联反应的自加速特性使得该方法能够在存在过量摩尔量的DIBOD小连接体与叠氮端基聚合物构建块的情况下高效地制备纯聚合物二聚体。第三，DSPAAC偶联反应的点击特性有助于在非常温和的环境反应条件下进行二聚化反应。因此，该方法为制备具有对称分子结构的拓扑聚合物，如嵌段、星形和树枝状聚合物，提供了一个强大的工具。
