Blennow M, Granström M, Olin P, Tiru M, Jäätmaa E, Askelöf P, Sato Y
Dev Biol Stand. 1986;65:185-90.
In the search for a new and better pertussis vaccine for general vaccination in Sweden, a clinical trial of an adsorbed acellular vaccine from Japan has been performed. The vaccine used was produced by Biken and contained only F-HA and the toxoid of pertussis toxin (LPF). The aims were: To demonstrate the serological response to primary vaccination of this adsorbed acellular vaccine in comparison to a plain whole cell vaccine. To compare the incidence of side reactions between the two types of vaccines and the adjuvant (aluminium phosphate) of the acellular vaccine used as placebo.
在瑞典寻找一种用于普通疫苗接种的新型且更好的百日咳疫苗时，对一种来自日本的吸附无细胞疫苗进行了一项临床试验。所使用的疫苗由日本大阪大学微生物病研究所生产，仅包含丝状血凝素（F-HA）和百日咳毒素类毒素（LPF）。目的是：与普通全细胞疫苗相比，证明这种吸附无细胞疫苗初次接种后的血清学反应。比较两种疫苗之间的副作用发生率以及用作安慰剂的无细胞疫苗佐剂（磷酸铝）的副作用发生率。
