Facile synthesis of -acylhydroxamates reaction of oxime chlorides with carboxylic acids.

A simple and efficient method for the synthesis of -acylhydroxamate derivatives from oxime chlorides and carboxylic acids was developed. The reaction affords clean and facile access to diverse -acylhydroxamates in high yields (up to 85%). The chemical structure of a typical product was confirmed using single-crystal X-ray structure analysis.