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催乳素在宫颈癌中的免疫细胞化学定位。

Immunocytochemical localization of prolactin in carcinoma of the cervix.

作者信息

Macfee M S, McQueen J, Strayer D E

出版信息

Gynecol Oncol. 1987 Mar;26(3):314-8. doi: 10.1016/0090-8258(87)90023-0.

DOI:10.1016/0090-8258(87)90023-0
PMID:3549475
Abstract

Immunocytochemical methods were used to demonstrate prolactin in both normal and malignant human cervices. Four of five cervices with epidermoid carcinoma and three of four cervices with adenocarcinoma demonstrated prolactin. One of four normal cervices stained positive for prolactin in the endocervical glands. Four cervices from pregnant patients were positive for prolactin. The results of this study show prolactin in human cervical carcinomas. The role and source of cervical prolactin is unknown.

摘要

采用免疫细胞化学方法在正常和恶性人宫颈组织中检测催乳素。五例表皮样癌宫颈组织中有四例、四例腺癌宫颈组织中有三例检测到催乳素。四例正常宫颈组织中有一例在内宫颈腺体内催乳素染色呈阳性。四例妊娠患者的宫颈组织催乳素检测呈阳性。本研究结果显示人宫颈癌组织中存在催乳素。宫颈催乳素的作用和来源尚不清楚。

相似文献

1
Immunocytochemical localization of prolactin in carcinoma of the cervix.催乳素在宫颈癌中的免疫细胞化学定位。
Gynecol Oncol. 1987 Mar;26(3):314-8. doi: 10.1016/0090-8258(87)90023-0.
2
Immunocytochemical localization of keratin in normal, dysplastic and neoplastic cervical epithelium.角蛋白在正常、发育异常及肿瘤性宫颈上皮中的免疫细胞化学定位。
Gynecol Obstet Invest. 1984;18(1):1-5. doi: 10.1159/000299040.
3
[An immunohistochemical study of the distribution of epithelial membrane antigen (EMA) in uterine carcinoma].
Nihon Sanka Fujinka Gakkai Zasshi. 1987 May;39(5):739-45.
4
A new marker of maturation in the cervix: the estrogen-regulated 24K protein.
Obstet Gynecol. 1986 Dec;68(6):825-31.
5
Is it safe to prescribe hormonal contraception and replacement therapy to patients with premalignant and malignant uterine cervices?
Gynecol Oncol. 1989 Aug;34(2):159-63. doi: 10.1016/0090-8258(89)90133-9.
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Localization of an estrogen-responsive protein in the human cervix during menstrual cycle, pregnancy, and menopause and in abnormal cervical epithelia without atypia.
Am J Obstet Gynecol. 1986 Nov;155(5):1090-6. doi: 10.1016/0002-9378(86)90357-1.
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[Immunohistochemical studies on epidermal growth factor receptor in oncogenesis of uterine cervical cancer].
Nihon Sanka Fujinka Gakkai Zasshi. 1989 Sep;41(9):1401-8.
8
[Immunohistochemical localization of keratin and secretory component in carcinoma of the uterine cervix].
Nihon Sanka Fujinka Gakkai Zasshi. 1985 Mar;37(3):359-64.
9
[Cytochemical determination of the protein sulfhydryl groups in the normal squamous epithelium, in erosion and in squamous cell carcinoma of the uterine cervix].[子宫颈正常鳞状上皮、糜烂及鳞状细胞癌中蛋白质巯基的细胞化学测定]
Vopr Onkol. 1974;20(8):17-21.
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1
HPV and Cervical Cancer: Molecular and Immunological Aspects, Epidemiology and Effect of Vaccination in Latin American Women.HPV 和宫颈癌:分子和免疫学方面、流行病学以及在拉丁美洲女性中的疫苗接种效果。
Viruses. 2024 Feb 21;16(3):327. doi: 10.3390/v16030327.
2
The Relevant Participation of Prolactin in the Genesis and Progression of Gynecological Cancers.催乳素在妇科癌症的发生和进展中的相关作用。
Front Endocrinol (Lausanne). 2021 Oct 21;12:747810. doi: 10.3389/fendo.2021.747810. eCollection 2021.
3
STAT3 activation is required for the antiapoptotic effects of prolactin in cervical cancer cells.
STAT3激活是催乳素在宫颈癌细胞中发挥抗凋亡作用所必需的。
Cancer Cell Int. 2015 Sep 4;15:83. doi: 10.1186/s12935-015-0234-9. eCollection 2015.
4
Prolactin and prolactin receptor expression in cervical intraepithelial neoplasia and cancer.催乳素及其受体在宫颈上皮内瘤变和癌症中的表达
Pathol Oncol Res. 2015 Apr;21(2):241-6. doi: 10.1007/s12253-014-9814-6. Epub 2014 Jul 3.
5
High expression of prolactin receptor is associated with cell survival in cervical cancer cells.催乳素受体的高表达与宫颈癌细胞的存活有关。
Cancer Cell Int. 2013 Oct 22;13(1):103. doi: 10.1186/1475-2867-13-103.
6
Distribution of epithelial antigens in the human uterine cervix: a review.人子宫颈上皮抗原的分布:综述
Arch Gynecol Obstet. 1989;246(2):61-84. doi: 10.1007/BF00934123.