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Leucomethylene blue probe detects a broad spectrum of reactive oxygen and nitrogen species.

作者信息

Cremer Christopher, Merkes Jean Michél, Bub Christina L, Rommel Dirk, Patureau Frederic W, Banala Srinivas

机构信息

Institute of Organic Chemistry, RWTH Aachen University Landoltweg 1 Aachen Germany.

Institute for Experimental Molecular Imaging, University Clinic, RWTH Aachen Forckenbeckstrasse 55 Germany

出版信息

RSC Adv. 2021 Sep 29;11(51):32295-32299. doi: 10.1039/d1ra06498c. eCollection 2021 Sep 27.

Abstract

Reactive oxygen and nitrogen species (ROS, RNS) are ubiquitous in biology with a variety of physiological and pathological functions. Here we describe a broad spectrum ROS/RNS detecting fluorogenic probe with red fluorescence emission and up to 100-fold gain. Hence these modified probes are useful for non-invasive quantification of ROS/RNS.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9590/9041740/8b33412d2c02/d1ra06498c-f1.jpg

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