Ungureanu Loredana, Vasilovici Alina, Șenilă Simona Corina, Cosgarea Ioana, Boda Daniel
Department of Dermatology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Department of Dermatology, Cluj-Napoca Emergency County Hospital, 400006 Cluj-Napoca, Romania.
Exp Ther Med. 2022 Jun;23(6):377. doi: 10.3892/etm.2022.11304. Epub 2022 Apr 7.
Cutaneous lymphomas are a group of rare and distinct diseases that present varying clinical manifestations, histopathology and prognosis. Optimal and early management relies on accurate diagnosis. Unfortunately, clinical diagnosis in early stages is difficult due to the clinical overlap with other dermatologic conditions. In numerous cases, several consultations and multiple biopsies are required. Dermoscopy is frequently used for the evaluation of melanocytic skin tumors, but its value has been recognized for non-melanocytic neoplasms and inflammatory skin diseases, and in the last few years it has assisted with the diagnosis of cutaneous lymphoproliferative disorders (LPD). Studies have shown that dermoscopy may be useful in the evaluation of cutaneous lymphomas, offering a link between clinical and histopathological examination, but the features are not diagnostic and histopathological confirmation is mandatory. However, dermoscopy can raise suspicion of cancer, leading to a skin biopsy. Furthermore, larger and prospective studies are required to define the exact dermoscopic features of every subtype of cutaneous lymphoma.
皮肤淋巴瘤是一组罕见且独特的疾病,具有不同的临床表现、组织病理学特征和预后。最佳的早期管理依赖于准确的诊断。不幸的是,由于与其他皮肤病在临床上存在重叠,早期临床诊断较为困难。在许多情况下,需要多次会诊和多次活检。皮肤镜常用于评估黑素细胞性皮肤肿瘤,但其在非黑素细胞性肿瘤和炎症性皮肤病中的价值也已得到认可,并且在过去几年中,它有助于诊断皮肤淋巴增殖性疾病(LPD)。研究表明,皮肤镜在评估皮肤淋巴瘤方面可能有用,它为临床检查和组织病理学检查之间提供了联系,但其特征并无诊断性,组织病理学确认是必需的。然而,皮肤镜可引发对癌症的怀疑,从而导致进行皮肤活检。此外,需要开展更大规模的前瞻性研究来明确皮肤淋巴瘤各亚型的确切皮肤镜特征。