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激光消融成功治疗原发性皮肤CD4小/中型T细胞淋巴增殖性疾病结节:一例报告及文献复习

Primary cutaneous CD4 small/medium T-cell lymphoproliferative disorder nodule successfully treated with laser Co ablation: a case report and literature review.

作者信息

Zengarini Corrado, Guglielmo Alba, Mussi Martina, Filippini Andrea, Vaccari Sabina, Piraccini Bianca Maria, Pileri Alessandro

机构信息

Department of Medical Sciences and Surgery, University of Bologna.

Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna.

出版信息

Dermatol Reports. 2024 Feb 6;16(4):9884. doi: 10.4081/dr.2024.9884. eCollection 2024 Nov 21.

DOI:10.4081/dr.2024.9884
PMID:39669877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11632454/
Abstract

This case report describes an 83-year-old patient with a history of non-melanoma skin cancer who presented with a violaceous, painless nodule on the neck. Dermoscopic examination and subsequent biopsy revealed a Small/Medium CD4 T-cell lymphoproliferative disorder (SMPLPD) of the skin. Although excision was initially recommended, the patient opted for treatment with CO laser ablation. The procedure had some minor complications but resulted in successful healing. SMPLPDs are a rare skin condition with limited treatment data, and this case suggests that CO laser ablation with minimal margins could be a viable alternative for selected patients, reducing bleeding and promoting second-intention healing for small nodules. However, more extensive follow-up data for SMPLPD cases are needed to understand long-term outcomes better.

摘要

本病例报告描述了一名83岁有非黑色素瘤皮肤癌病史的患者,其颈部出现一个紫罗兰色、无痛性结节。皮肤镜检查及随后的活检显示为皮肤小/中型CD4 T细胞淋巴增殖性疾病(SMPLPD)。尽管最初建议进行切除,但患者选择了CO2激光消融治疗。该手术有一些轻微并发症,但最终成功愈合。SMPLPD是一种罕见的皮肤疾病,治疗数据有限,该病例表明,对于选定的患者,采用最小切缘的CO2激光消融可能是一种可行的替代方法,可减少出血并促进小结节的二期愈合。然而,需要更广泛的SMPLPD病例随访数据,以更好地了解长期预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6acc/11632454/8448385f9b65/dr-16-4-9884-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6acc/11632454/8448385f9b65/dr-16-4-9884-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6acc/11632454/8448385f9b65/dr-16-4-9884-g001.jpg

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本文引用的文献

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Clinical features and treatment outcomes for primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder: a retrospective cohort study from the Dana-Farber Cancer Institute and updated literature review.原发性皮肤CD4+小/中T细胞淋巴增殖性疾病的临床特征及治疗结果:一项来自丹娜法伯癌症研究所的回顾性队列研究及文献综述更新
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Arch Craniofac Surg. 2021 Aug;22(4):199-203. doi: 10.7181/acfs.2021.00199. Epub 2021 Aug 20.
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Prominent Blasts in Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorder. A Reconsideration of Diagnostic Criteria.原发性皮肤CD4+小/中T细胞淋巴增殖性疾病中的显著母细胞。诊断标准的重新考量。
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