Ji Lei, Gu Guangchao, Liu Zhili, Chen Yuexin, Ye Wei, Liu Bao, Liu Changwei, Zheng Yuehong
Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Vascular Surgery, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Front Surg. 2022 Apr 14;9:873665. doi: 10.3389/fsurg.2022.873665. eCollection 2022.
Iliac arteriovenous fistulas (IAVFs) are rare abnormalities with limited reported cases. This study aimed to summarize the clinical features and experiences on the diagnosis and endovascular treatment of IAVFs.
A single-center retrospective study of IAVFs from 2010 to 2019 was performed. Data including demographics, clinical characteristics, radiological images, surgical details, and follow-up were collected.
A total of 16 patients diagnosed with IAVFs were identified. The female to male ratio was 3:1. The mean age was 47.7 ± 10.4 years (range: 35-73 years). Leg swelling and cardiac insufficiency, especially heart failure, were the most common primary symptoms in this series, which were revealed in 68.8 and 37.5% of patients, respectively. Iatrogenic, traumatic, and congenital IAVFs were diagnosed in 62.5, 12.5, and 25.0% of patients, respectively, among which hysterectomy was thought to be the main cause for female iatrogenic IAVFs (31.3%). Anatomic analysis found that internal iliac vessels were the predilected sites of IAVFs. All the patients were treated by endovascular procedures composed of transarterial embolization (50.0%), transarterial and stage II transvenous embolization (31.3%), stage I transarterial and transvenous embolization (12.5%), and transarterial embolization plus stent implantation (6.3%). The clinical success rate was 93.8%. Minor complications including fever (18.8%) and exudation at the puncture point (6.25%) were noted and well-treated. During a follow-up period of 51.3 ± 41.9 months after operations, only one patient experienced re-emergence of heart failure because of recurrence of leiomyosarcoma; other patients recovered uneventfully with symptoms relief and no severe embolization-related complications was encountered.
IAVFs are rare disorders and correct diagnosis requires careful history taking and physical examination, combined with proper imaging investigation. The primary goal for treatment of IAVFs was to relieve associated symptoms. Based on the results of this study, endovascular approach is safe and effective for treatment of IAVFs.
髂动静脉瘘(IAVF)是一种罕见的异常情况,报告的病例有限。本研究旨在总结IAVF的临床特征以及诊断和血管内治疗的经验。
对2010年至2019年的IAVF进行单中心回顾性研究。收集了包括人口统计学、临床特征、放射影像、手术细节和随访等数据。
共确定了16例诊断为IAVF的患者。男女比例为3:1。平均年龄为47.7±10.4岁(范围:35 - 73岁)。腿部肿胀和心脏功能不全,尤其是心力衰竭,是本系列中最常见的主要症状,分别在68.8%和37.5%的患者中出现。医源性、创伤性和先天性IAVF分别在62.5%、12.5%和25.0%的患者中被诊断出,其中子宫切除术被认为是女性医源性IAVF的主要原因(31.3%)。解剖分析发现,髂内血管是IAVF的好发部位。所有患者均接受了血管内手术治疗,包括经动脉栓塞(50.0%)、经动脉和二期经静脉栓塞(31.3%)、一期经动脉和经静脉栓塞(12.5%)以及经动脉栓塞加支架植入(6.3%)。临床成功率为93.8%。记录到的轻微并发症包括发热(18.8%)和穿刺点渗血(6.25%),且均得到良好治疗。在术后51.3±41.9个月的随访期内,只有1例患者因平滑肌肉瘤复发而再次出现心力衰竭;其他患者症状缓解,恢复顺利,未出现严重的栓塞相关并发症。
IAVF是罕见疾病,正确诊断需要仔细询问病史和体格检查,并结合适当的影像学检查。IAVF治疗的主要目标是缓解相关症状。基于本研究结果,血管内治疗方法对IAVF的治疗是安全有效的。