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Editorial: Insights in Pharmacogenetics and Pharmacogenomics: 2021.

作者信息

Agúndez José A G, García-Martín Elena

机构信息

Universidad de Extremadura, Institute of Molecular Pathology Biomarkers, University of Extremadura, Cáceres, Spain.

出版信息

Front Pharmacol. 2022 Apr 14;13:907131. doi: 10.3389/fphar.2022.907131. eCollection 2022.

DOI:10.3389/fphar.2022.907131
PMID:35496282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9046651/
Abstract
摘要

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本文引用的文献

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Knockout of human arylamine N-acetyltransferase 1 (NAT1) in MDA-MB-231 breast cancer cells leads to increased reserve capacity, maximum mitochondrial capacity, and glycolytic reserve capacity.敲除人芳香胺 N-乙酰基转移酶 1（NAT1）在 MDA-MB-231 乳腺癌细胞中导致储备能力增加、最大线粒体能力和糖酵解储备能力增加。
Mol Carcinog. 2018 Nov;57(11):1458-1466. doi: 10.1002/mc.22869. Epub 2018 Jul 18.
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Economic Utility: Combinatorial Pharmacogenomics and Medication Cost Savings for Mental Health Care in a Primary Care Setting.经济效用：基层医疗环境中用于精神卫生保健的组合药物基因组学与药物成本节约
Clin Ther. 2017 Mar;39(3):592-602.e1. doi: 10.1016/j.clinthera.2017.01.022. Epub 2017 Feb 21.
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Combinatorial Versus Individual Gene Pharmacogenomic Testing in Mental Health: A Perspective on Context and Implications on Clinical Utility.心理健康领域中组合基因与个体基因药物基因组学检测：关于背景及临床效用影响的观点
Yale J Biol Med. 2015 Nov 24;88(4):375-82. eCollection 2015 Dec.
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Contribution of bleeding and thromboembolic events to in-hospital mortality among patients with thrombocytopenia treated with heparin.肝素治疗的血小板减少症患者中出血和血栓栓塞事件对院内死亡率的影响
Am J Cardiol. 2009 Jul 15;104(2):292-7. doi: 10.1016/j.amjcard.2009.03.034. Epub 2009 Jun 3.
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Polymorphisms of human N-acetyltransferases and cancer risk.人类N-乙酰基转移酶的多态性与癌症风险
Curr Drug Metab. 2008 Jul;9(6):520-31. doi: 10.2174/138920008784892083.
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Combinatorial pharmacogenetics.组合药物遗传学
Nat Rev Drug Discov. 2005 Nov;4(11):911-8. doi: 10.1038/nrd1874.
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N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis.N-乙酰转移酶遗传学及其在芳香族和杂环胺诱导致癌易感性中的作用。
Toxicol Lett. 2000 Mar 15;112-113:349-56. doi: 10.1016/s0378-4274(99)00226-x.
8
Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.重组人NAT1和多态性NAT2乙酰基转移酶对芳胺致癌物的代谢激活与失活作用。
Carcinogenesis. 1993 Aug;14(8):1633-8. doi: 10.1093/carcin/14.8.1633.