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胰腺内副脾中的表皮样囊肿，囊肿液中癌胚抗原水平异常升高：一例报告。

Epidermoid cyst in an intrapancreatic accessory spleen with abnormally high CEA level in cyst fluid: a case report.

作者信息

Lo Chun-Hai, Tsang Po-Man, Cheng Shui-Ying, Ling Cheuk-Nam, Ho Cheuk-Lam

机构信息

United Christian Hospital, Department of Pathology, Hong Kong, China.

CUHK Medical Centre, Department of Pathology, Hong Kong, China.

出版信息

Autops Case Rep. 2022 Apr 14;12:e2021369. doi: 10.4322/acr.2021.369. eCollection 2022.

DOI:10.4322/acr.2021.369
PMID:35496737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9037849/
Abstract

Epidermoid cyst in an intrapancreatic accessory spleen is a rare benign lesion that is difficult to diagnose preoperatively. Cyst fluid analysis for biochemistry markers has been widely used to aid the diagnosis of pancreatic cysts. A high cyst fluid carcinoembryonic antigen (CEA) level (>800 ng/mL) is said to be useful in distinguishing intraductal papillary mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN) from other non-mucinous cysts. We herein report a case of epidermoid cyst in an intrapancreatic accessory spleen with abnormally high CEA level (3582 ng/mL) in the cyst fluid, suggesting a potential pitfall in using cyst fluid CEA level as an indicator of mucinous neoplasms.

摘要

胰腺内副脾中的表皮样囊肿是一种罕见的良性病变，术前难以诊断。囊肿液生化标志物分析已广泛用于辅助胰腺囊肿的诊断。据说囊肿液癌胚抗原（CEA）水平高（>800 ng/mL）有助于将导管内乳头状黏液性肿瘤（IPMN）和黏液性囊性肿瘤（MCN）与其他非黏液性囊肿区分开来。我们在此报告一例胰腺内副脾中的表皮样囊肿，其囊肿液中CEA水平异常高（3582 ng/mL），提示将囊肿液CEA水平用作黏液性肿瘤指标时可能存在陷阱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/a5a815def959/autopsy-12-e2021369-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/c0acb6ae0cbb/autopsy-12-e2021369-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/612fc42cc67e/autopsy-12-e2021369-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/bce0b1a2fb0f/autopsy-12-e2021369-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/d50288b35e40/autopsy-12-e2021369-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/a5a815def959/autopsy-12-e2021369-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/c0acb6ae0cbb/autopsy-12-e2021369-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/612fc42cc67e/autopsy-12-e2021369-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/bce0b1a2fb0f/autopsy-12-e2021369-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/d50288b35e40/autopsy-12-e2021369-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd3/9037849/a5a815def959/autopsy-12-e2021369-g05.jpg

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本文引用的文献

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Epidermoid cyst in an intrapancreatic accessory spleen in the pancreas head: a case report.胰腺头部胰内副脾的表皮样囊肿：一例报告。
BMC Gastroenterol. 2020 Nov 20;20(1):392. doi: 10.1186/s12876-020-01540-4.
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Epidermoid cyst within an intrapancreatic accessory spleen exhibiting abrupt changes in serum carbohydrate antigen 19-9 level: a case report.胰腺内副脾伴表皮样囊肿致血清糖类抗原19-9水平突然变化：一例报告
Surg Case Rep. 2020 Jun 12;6(1):133. doi: 10.1186/s40792-020-00892-z.
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The prevalence and morphometry of an accessory spleen: A meta-analysis and systematic review of 22,487 patients.
副脾的发生率和形态计量学：22487 例患者的荟萃分析和系统评价。
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Epidermoid Cyst in an Intrapancreatic Accessory Spleen: Case Report and Literature Review of the Preoperative Imaging Findings.胰腺内副脾表皮样囊肿：病例报告及术前影像学表现的文献综述
Intern Med. 2016;55(23):3445-3452. doi: 10.2169/internalmedicine.55.7140. Epub 2016 Dec 1.
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A recurrent epidermoid cyst of the spleen: report of a case and literature review.脾脏复发性表皮样囊肿：一例报告及文献复习
World J Surg Oncol. 2016 Apr 1;14:98. doi: 10.1186/s12957-016-0857-x.
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A case of epidermoid cyst in an intrapancreatic accessory spleen mimicking pancreas neoplasms: MRI with DWI.一例胰腺内副脾表皮样囊肿酷似胰腺肿瘤：磁共振成像扩散加权成像表现
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Cyst fluid amylase and CEA levels in the differential diagnosis of pancreatic cysts: a single-center experience with histologically proven cysts.胰液淀粉酶和癌胚抗原水平在胰腺囊肿鉴别诊断中的应用：单中心组织学确诊囊肿的经验
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Splenic epidermoid cyst - a rare entity.脾表皮样囊肿——一种罕见的病症。
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