Tolerance mechanism of to Pb: response changes of related active ingredients under Pb stress.

ZZY has good tolerance to Pb, but the tolerance mechanism is not clear. The manuscript aimed to clarify the tolerance mechanism from the perspective of the response changes of related active ingredients. The synthesis of polysaccharides, proteins and thiol compounds in can be accelerated with Pb stress. Under Pb stress, can synthesize oxalic acid and secrete it extracellularly. In addition, high concentration of Pb can inhibit the synthesis and extracellular secretion of formic acid and malic acid. The tolerance of to Pb is the results of multiple reactions. The Pb can promote the synthesis of polysaccharides, proteins, thiol compounds and oxalic acid. In the early stage of Pb stress, can rapidly initiate an extracellular emergency mechanism, synthesize oxalic acid in mycelia and secrete it extracellularly to remove free Pb and alleviate the toxicity of Pb to cells. With the transport of Pb into cells, it can promote the synthesis of polysaccharides, proteins, thiol compounds to adsorb and transform the Pb and ease the damage to the cells. The manuscript provides theoretical support and scientific explanation for the application of .