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Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.2016 年全球 195 个国家/地区下呼吸道感染的发病率、死亡率和病因的全球、区域和国家估计值：2016 年全球疾病负担研究的系统分析。
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万隆三级医院儿童急性下呼吸道感染概况：新冠疫情之前和期间有差异吗？

Acute Lower Respiratory Infection Profile in Children at Tertiary Hospital Bandung: Is There a Difference Before and During COVID-19 Pandemic?

作者信息

Majeda Allisa, Nataprawira Heda Melinda, Idjradinata Ponpon

机构信息

Departement of Child Health, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.

出版信息

Glob Pediatr Health. 2022 Apr 25;9:2333794X221085393. doi: 10.1177/2333794X221085393. eCollection 2022.

DOI:10.1177/2333794X221085393
PMID:35498368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9052809/
Abstract

This study aims to analyze differences of the prevalence and characteristics of acute lower respiratory infection (ALRI) in children at tertiary hospital before and during COVID-19 pandemic. This was an observational analytic study with cross-sectional design involving pediatric patients based on the time of the study which was in 1 year-prepandemic (A) and 1 year-pandemic period (B). For period A inpatient data were retrieved from medical records and period B used pediatric ALRI registry. The ALRI characteristics were analyzed with significance if < .05. Prevalence in periods A and B were 5.8% (534/9252) and 4.9% (409/8283), respectively. The characteristics of ALRI for clinical, comorbidities, laboratory findings (NLR, TLC), and chest radiograph showed significant differences ( < .05). ALRI as manifestation of confirmed COVID-19 were identified in 16 (4.9%) cases. Prevalence of ALRI in children during COVID-19 pandemic is lower compared to before. There are differences in the characteristics of ALRI in pediatrics.

摘要

本研究旨在分析新冠疫情之前及期间，三级医院儿童急性下呼吸道感染（ALRI）的患病率及特征差异。这是一项采用横断面设计的观察性分析研究，根据研究时间，纳入了1年疫情前（A组）和1年疫情期间（B组）的儿科患者。A组的住院患者数据从病历中获取，B组则使用儿科ALRI登记册。若P<0.05，则对ALRI特征进行显著性分析。A组和B组的患病率分别为5.8%（534/9252）和4.9%（409/8283）。ALRI在临床、合并症、实验室检查结果（中性粒细胞与淋巴细胞比值、白细胞计数）及胸部X光片方面的特征存在显著差异（P<0.05）。确诊为新冠的病例中有16例（4.9%）表现为ALRI。新冠疫情期间儿童ALRI的患病率低于疫情前。儿科ALRI的特征存在差异。