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生活方式调整与多囊卵巢综合征:旧话新说。

Life Modifications and PCOS: Old Story But New Tales.

机构信息

Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai, China.

Department of Gynecology, The Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.

出版信息

Front Endocrinol (Lausanne). 2022 Apr 13;13:808898. doi: 10.3389/fendo.2022.808898. eCollection 2022.

Abstract

Polycystic ovary syndrome (PCOS) is defined as a kind of endocrine and metabolic disorder that affects female individuals of reproductive age. Lifestyle modifications, including diet modifications, exercise, and behavioral modification, appear to alleviate the metabolic dysfunction and improve the reproductive disorders of PCOS patients (particularly in obese women). Therefore, lifestyle modifications have been gradually acknowledged as the first-line management for PCOS, especially in obese patients with PCOS. However, the mechanism of lifestyle modifications in PCOS, the appropriate composition of diet modifications, and the applicable type of exercise modifications for specific female populations are rarely reported. We conducted a systematic review and enrolled 10 randomized controlled trials for inclusion in a certain selection. In this review, we summarized the existing research on lifestyle modifications in PCOS. We aimed to illustrate the relationship between lifestyle modifications and PCOS (referring to hyperandrogenism, insulin resistance as well as obesity) and also considered the priorities for future research. These results might be an invaluable tool to serve as a guide in lifestyle modifications as the intervention for PCOS and other related endocrine disorders.

摘要

多囊卵巢综合征(PCOS)被定义为一种影响生殖年龄女性的内分泌和代谢紊乱。生活方式的改变,包括饮食改变、运动和行为改变,似乎可以缓解 PCOS 患者的代谢功能障碍并改善生殖障碍(尤其是肥胖女性)。因此,生活方式的改变已逐渐被认为是 PCOS 的一线治疗方法,尤其是对于肥胖的 PCOS 患者。然而,生活方式改变在 PCOS 中的作用机制、饮食改变的适当组成以及特定女性人群适用的运动改变类型很少有报道。我们进行了系统评价,纳入了 10 项随机对照试验进行特定选择。在本次综述中,我们总结了现有关于 PCOS 生活方式改变的研究。我们旨在说明生活方式改变与 PCOS(包括高雄激素血症、胰岛素抵抗和肥胖)之间的关系,并考虑未来研究的重点。这些结果可能是一个非常宝贵的工具,可以作为 PCOS 及其他相关内分泌紊乱的干预措施中生活方式改变的指南。

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