Mukamel E, Engelstein D, Simon D, Servadio C
J Urol (Paris). 1987;93(1):31-3.
A randomized, double-blind study was carried out on forty patients with acute renal colic in order to evaluate the efficacy of Rowatinex in the treatment of patients with ureteric stones. Patients were randomized to Rowatinex and placebo tablets. In the Rowatinex-treated patients there was a significantly higher rate of expulsion of stones which were greater than or equal to 3 mm in diameter when compared with the placebo group (61% vs. 28%, respectively). A higher success rate (spontaneous stone expulsion and/or disappearance of dilatation of the collecting system on IVU) was noted in the Rowatinex group when compared to the placebo group (78% vs. 52%, respectively), although this was not statistically significant. No significant side effects were noted during the treatment with Rowatinex.
为评估罗瓦廷克斯（Rowatinex）治疗输尿管结石患者的疗效，对40例急性肾绞痛患者进行了一项随机双盲研究。患者被随机分为罗瓦廷克斯组和安慰剂组。与安慰剂组相比，接受罗瓦廷克斯治疗的患者中直径大于或等于3mm的结石排出率显著更高（分别为61%和28%）。与安慰剂组相比，罗瓦廷克斯组的成功率更高（结石自发排出和/或静脉肾盂造影显示集合系统扩张消失）（分别为78%和52%），尽管这在统计学上无显著差异。在使用罗瓦廷克斯治疗期间未观察到明显的副作用。
