Copperthwaite Amy, Sahebally Shaheel Mohammad, Raza Zeeshan Muhammad, Devane Liam, McCawley Niamh, Kearney David, Burke John, McNamara Deborah
Department of Colorectal Surgery, Beaumont Hospital, 9, Dublin, Ireland.
Royal College of Surgeons, St Stephen's Green, Dublin 2, Dublin, Ireland.
Ir J Med Sci. 2023 Apr;192(2):795-803. doi: 10.1007/s11845-022-03017-7. Epub 2022 May 2.
Enhanced recovery programmes in laparoscopic colorectal surgery (LCS) employ combined approaches to achieve postoperative analgesia. Transversus abdominis plane (TAP) block is a locoregional anaesthetic technique that may reduce postoperative pain.
To perform a systematic review and meta-analysis to compare the effectiveness of laparoscopic- versus ultrasound-guided TAP block in LCS.
Databases were searched for relevant articles from inception until March 2022. All randomised controlled trials (RCTs) that compared laparoscopic (LTB) versus ultrasound-guided (UTB) TAP blocks in LCS were included. The primary outcome was narcotic consumption at 24 h postoperatively, whilst secondary outcomes included pain scores at 24 h postoperatively, operative time, postoperative nausea and vomiting (PONV) and complication rates. Random effects models were used to calculate pooled effect size estimates.
Three RCTs were included capturing 219 patients. Studies were clinically heterogenous. On random effects analysis, LTB was associated with significantly lower narcotic consumption (SMD - 0.30 mg, 95% CI = - 0.57 to - 0.03, p = 0.03) and pain scores (SMD - 0.29, 95% CI = - 0.56 to - 0.03, p = 0.03) at 24 h. However, there were no differences in operative time (SMD - 0.09 min, 95% CI = - 0.40 to 0.22, p = 0.56), PONV (OR = 0.97, 95% CI = 0.36 to 2.65, p = 0.96) or complication (OR = 1.30, 95% CI = 0.64 to 2.64, p = 0.47) rates.
LTB is associated with significantly less narcotic usage and pain at 24 h postoperatively but similar PONV, operative time and complication rates, compared to UTB. However, the data were inconsistent, and our findings require further investigation. LTB obviates the need for ultrasound devices whilst also decreasing procedure logistical complexity.
腹腔镜结直肠手术(LCS)中的加速康复计划采用综合方法实现术后镇痛。腹横肌平面(TAP)阻滞是一种局部麻醉技术,可能会减轻术后疼痛。
进行系统评价和荟萃分析,比较腹腔镜引导与超声引导下TAP阻滞在LCS中的有效性。
检索数据库中从起始至2022年3月的相关文章。纳入所有比较LCS中腹腔镜引导(LTB)与超声引导(UTB)TAP阻滞的随机对照试验(RCT)。主要结局是术后24小时的麻醉药物消耗量,次要结局包括术后24小时的疼痛评分、手术时间、术后恶心呕吐(PONV)和并发症发生率。采用随机效应模型计算合并效应量估计值。
纳入3项RCT,共219例患者。研究在临床方面存在异质性。随机效应分析显示,LTB组术后24小时的麻醉药物消耗量(标准化均数差[SMD]为-0.30mg,95%置信区间[CI]=-0.57至-0.03,p=0.03)和疼痛评分(SMD为-0.29,95%CI=-0.56至-0.03,p=0.03)显著更低。然而,手术时间(SMD为-0.09分钟,95%CI=-0.40至0.22,p=0.56)、PONV(比值比[OR]=0.97,95%CI=0.36至2.65,p=0.96)或并发症发生率(OR=1.30,95%CI=0.64至2.64,p=0.47)无差异。
与UTB相比,LTB术后24小时的麻醉药物使用量和疼痛显著更少,但PONV、手术时间和并发症发生率相似。然而,数据并不一致,我们的研究结果需要进一步调查。LTB无需超声设备,同时还降低了手术后勤复杂性。