Stanford University School of Medicine (M.X.).
Arthroscopy. 2022 May;38(5):1535-1536. doi: 10.1016/j.arthro.2021.11.022.
Soaking anterior cruciate ligament grafts in vancomycin solution is done by many surgeons. Research has indicated decreased infection rates and similar anterior cruciate ligament retear rates between grafts soaked in vancomycin solution before implantation versus those without. In addition, there has been basic science evidence for tenocyte survival and viability even when exposed to vancomycin solution. The next frontier, investigating the maturation of vancomycin-soaked grafts with advanced imaging, may cause some surgeons to reconsider the practice but should not stop it, based on the available literature.
许多外科医生会将前交叉韧带移植物浸泡在万古霉素溶液中。研究表明，与未浸泡万古霉素溶液的移植物相比，浸泡后的移植物感染率降低，前交叉韧带再撕裂率相似。此外，即使万古霉素溶液暴露，也有科学证据表明腱细胞能够存活。接下来的前沿研究是通过先进的成像技术来研究万古霉素浸泡的移植物的成熟度，这可能会促使一些外科医生重新考虑这一做法，但根据现有文献，这不应该停止这种做法。
