J Am Pharm Assoc (2003). 2022 Jul-Aug;62(4S):S22-S28. doi: 10.1016/j.japh.2022.04.007. Epub 2022 Apr 14.
More than 191 million opioid prescriptions were filled in the United States during 2017, and studies have shown that patients often have leftover medication.
To (1) measure the percentage filled as partial quantities and the percentage subsequently filled to completion; (2) determine which medications are filled as partial, completion, and full fills; and (3) identify patient reasons and demographics for partial, completion, and full fills.
Two pharmacies of a national community pharmacy chain in Richmond, VA.
Virginia law allows prescriptions to be filled in partial quantities as long as the total quantity does not exceed the written quantity and the remaining portions are filled within 30 days of the written date. Pharmacists developed an intervention to educate patients about the option to fill opioid prescriptions as a partial quantity.
Retrospective analysis of drug utilization reports to identify the impact of the pharmacist intervention for acute, nonmaintenance opioid prescriptions filled as partial, completion, or full fill during a 5-month period. Patient demographics and reasons for choosing a partial or full fill were collected using surveys completed at prescription pickup.
A total of 25.6% of included prescriptions were partially filled, and of these, only 31.9% were filled to completion. Hydrocodone-acetaminophen was the most common prescription, 35.8% full, 28.3% partial, and 36.4% completion fills. Patients' motivation was driven by the pharmacist's suggestion (48.5%) for partial fill and desire to have the medication if needed (36.6%) for full fill.
Pharmacist offer of partial filling of acute opioid prescriptions may lead patients to partially fill prescriptions, and patients cited the pharmacist suggestion as a motivator.
2017 年,美国开出的阿片类药物处方超过 1.91 亿张,研究表明患者经常会有剩余药物。
(1)测量部分剂量和完整剂量的配药比例;(2)确定哪些药物是部分剂量、完整剂量和全剂量配药;(3)确定患者选择部分、完整和全剂量的原因和人口统计学特征。
弗吉尼亚州里士满的一家全国连锁社区药店的两家药店。
弗吉尼亚州的法律允许处方以部分剂量配药,只要总剂量不超过书面剂量,且剩余部分在书面日期后 30 天内配完即可。药剂师采取了一项干预措施,向患者宣传将阿片类药物处方以部分剂量配药的选择。
对药物利用报告进行回顾性分析,以确定在 5 个月期间,药剂师干预对急性非维持性阿片类药物处方部分、完整剂量配药的影响。在取药时,使用调查问卷收集患者的人口统计学特征和选择部分或全剂量的原因。
共有 25.6%的纳入处方被部分配药,其中只有 31.9%的处方被完整配药。氢可酮-对乙酰氨基酚是最常见的处方,全剂量占 35.8%,部分剂量占 28.3%,完整剂量占 36.4%。患者选择部分配药的动机是药剂师建议(48.5%),选择全剂量配药的动机是如果需要药物时方便使用(36.6%)。
药剂师提供急性阿片类药物处方的部分配药可能会促使患者部分配药,而患者则将药剂师的建议作为选择部分配药的动机。