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踝关节旋转骨折切开复位内固定术后慢性阻塞性肺疾病患者的30天发病率和死亡率

Thirty-Day Morbidity and Mortality in Patients With COPD Following Open Reduction and Internal Fixation for Rotational Ankle Fractures.

作者信息

Gupta Puneet, Quan Theodore, Abdo Magid G, Manzi Joseph E, Knapp Brock, Shaffer Gene

机构信息

Department of Orthopedic Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC.

Department of Orthopedic Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC.

出版信息

J Foot Ankle Surg. 2022 Nov-Dec;61(6):1275-1279. doi: 10.1053/j.jfas.2022.03.015. Epub 2022 Apr 7.

Abstract

Prior orthopedic literature has found patients with chronic obstructive pulmonary disease (COPD) to be at an increased risk for postoperative morbidity and mortality. Thus, the purpose of this study is to identify whether there are any differences in risk for 30-day morbidity or mortality following ORIF for ankle fractures between adult patients with COPD and without COPD. Patients undergoing operative treatment for ankle fracture were identified in the National Surgical Quality Improvement Program database from 2006 to 2018. Patients were divided into 2 cohorts: non-COPD and COPD patients. In this analysis, demographics data, medical comorbidities, and thirty-day postoperative outcomes were analyzed between the 2 cohorts. Bivariate and multivariate analyses were performed. Of 10,346 total patients who underwent operative treatment for ankle fracture, 9986 patients (96.5%) did not have a history of COPD whereas 360 (3.5%) had COPD. Following adjustment to control for demographic and comorbidity data, relative to patients without COPD, those with COPD had an increased risk of pneumonia (odds ratio [OR] 4.601; p = .001), unplanned intubation (OR 3.085; p = .043), and hospital readmission (OR 1.828; p = .020). Patients with COPD did not have a statistically significant difference with regards to mortality (OR 2.729; p = .080). Adult patients with COPD are at an increased risk for pneumonia, unplanned intubation, and hospital readmission within 30 days following ORIF of ankle fractures compared to patients without COPD. Despite these risks, this is a relatively safe procedure for these patients and the presence of COPD alone should not serve as a barrier to surgery.

摘要

既往骨科文献发现,慢性阻塞性肺疾病(COPD)患者术后发病和死亡风险增加。因此,本研究的目的是确定成年COPD患者和非COPD患者在踝关节骨折切开复位内固定术后30天发病或死亡风险上是否存在差异。在国家外科质量改进计划数据库中识别出2006年至2018年接受踝关节骨折手术治疗的患者。患者被分为两组:非COPD组和COPD组。在本分析中,对两组患者的人口统计学数据、合并症及术后30天的结局进行了分析。进行了双变量和多变量分析。在总共10346例接受踝关节骨折手术治疗的患者中,9986例(96.5%)无COPD病史,而360例(3.5%)有COPD病史。在对人口统计学和合并症数据进行调整后,与非COPD患者相比,COPD患者发生肺炎的风险增加(比值比[OR]4.601;p = 0.001)、非计划插管风险增加(OR 3.085;p = 0.043)以及再次入院风险增加(OR 1.828;p = 0.020)。COPD患者在死亡率方面无统计学显著差异(OR 2.729;p = 0.080)。与非COPD患者相比,成年COPD患者在踝关节骨折切开复位内固定术后30天内发生肺炎、非计划插管及再次入院的风险增加。尽管存在这些风险,但对于这些患者而言,这仍是一种相对安全的手术,仅COPD的存在不应成为手术的障碍。

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