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肋骨骨折固定有益于慢性阻塞性肺疾病患者:一项创伤质量改进计划研究。

Fixation of rib fractures is beneficial for patients with chronic obstructive pulmonary disease, a trauma quality improvement program study.

机构信息

Department of Trauma and Emergency Surgery, Linkou Medical Center, Chang Gung Memorial Hospital, No. 5, Fu-Hsing Street, Kwei-Shan District, Taoyuan, Taiwan.

Chang Gung University, Taoyuan, Taiwan.

出版信息

J Orthop Surg Res. 2024 Sep 28;19(1):588. doi: 10.1186/s13018-024-05065-4.

Abstract

BACKGROUND

Internal fixation for multiple rib fractures is well established. Patients with underlying chronic obstructive pulmonary disease (COPD) have a higher rate of perioperative complications. It is unclear if these patients are suitable candidates for internal fixation and if surgical interventions are harmful to these patients.

STUDY DESIGN AND METHODS

Adult patients with ≥ 3 rib fractures and underlying COPD from the Trauma Quality Improvement Program between 2017 and 2019 were eligible for inclusion. The patients were divided into two treatment groups: operative and non-operative. Furthermore, inverse probability treatment weighting was applied to analyze mortality and adverse hospital events.

RESULTS

Patients with COPD in the operative group had higher ventilator use (odds ratio [OR], 3.211; 95% confidence interval [CI], 1.993-5.175; p < 0.001). Additionally, they had a longer length of stay (coefficient β, 4.139; standard error, 0.829; p < 0.001) and longer ventilator days (coefficient β, 1.937; standard error, 0.655; p = 0.003) than in the non-operative group. Furthermore, the mortality rate was lower in the operative group than in the non-operative group (OR, 0.426; 95% CI, 0.228-0.798; p = 0.008).

CONCLUSION

Internal fixation of rib fractures plays a crucial role in patients with underlying COPD disease. They presented a better mortality rate without an increased perioperative complication rate.

摘要

背景

多发性肋骨骨折的内固定治疗已得到广泛认可。患有基础慢性阻塞性肺疾病(COPD)的患者围手术期并发症发生率较高。目前尚不清楚这些患者是否适合内固定治疗,以及手术干预是否对这些患者有害。

研究设计和方法

纳入 2017 年至 2019 年创伤质量改进计划中≥3 根肋骨骨折且患有基础 COPD 的成年患者。患者分为手术组和非手术组。此外,还应用逆概率治疗加权法分析死亡率和不良医院事件。

结果

手术组 COPD 患者呼吸机使用率更高(优势比 [OR],3.211;95%置信区间 [CI],1.993-5.175;p<0.001)。此外,他们的住院时间更长(系数β,4.139;标准误,0.829;p<0.001),呼吸机使用天数更长(系数β,1.937;标准误,0.655;p=0.003),而非手术组。此外,手术组的死亡率低于非手术组(OR,0.426;95%CI,0.228-0.798;p=0.008)。

结论

对于患有基础 COPD 疾病的患者,肋骨骨折的内固定治疗起着至关重要的作用。他们的死亡率更低,而围手术期并发症发生率没有增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5ee/11438050/28f45774c7f9/13018_2024_5065_Fig1_HTML.jpg

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