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司法治疗的1型糖尿病患者药物治疗随访的临床和人文影响。

Clinical and humanistic impact of pharmacotherapeutic follow-up in patients with type 1 diabetes mellitus treated judicially.

作者信息

Mendonça Thays S, Oliveira William N, Belo Vinícius S, Silva Eduardo S, Pereira Mariana L, Obreli-Neto Paulo R, Baldoni André O

机构信息

Programa de Pós-Graduação em Ciências da Saúde, Federal University of São João Del-Rei (UFSJ)-Campus Centro-Oeste Dona Lindu (CCO), Rua Sebastião Gonçalves Coelho, 400-Bairro Chanadour, Divinópolis, MG, CEP:35501-296, Brazil.

Departamento de Farmácia, Centro Universitário das Faculdades Integradas de Ourinhos (UniFIO), Rodovia BR-153, Km 338 S/N Água do Cateto, Ourinhos, SP, 19909-100, Brazil.

出版信息

Diabetol Metab Syndr. 2022 May 3;14(1):61. doi: 10.1186/s13098-022-00835-8.

DOI:10.1186/s13098-022-00835-8
PMID:35501843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9061226/
Abstract

BACKGROUND

There is a lack of studies that assess the effectiveness of pharmacotherapeutic follow-up in the context of the judicialization of insulin analogues.

AIMS

To evaluate the clinical and humanistic impact of pharmacotherapeutic follow-up in patients with type 1 diabetes mellitus who receive insulin analogues by judicial decision in a Brazilian municipality.

METHODS

A quasi-experimental study of the before-and-after type was carried out through pharmacotherapeutic follow-up. Patients who accepted to participate in the study underwent laboratory tests of glycemic and lipid profile before and after the intervention, and underwent five pharmaceutical consultations. In addition, quality of life and health, knowledge, and skills related to insulin application techniques were analyzed.

RESULTS

28 patients participated in all stages. Of these, most were female (53.6%), with a mean age of 32.8 ± 11.6 years. After the intervention, there was a reduction in blood glucose levels, blood pressure, and increased body mass index. In addition, there was greater knowledge and skills regarding insulin application techniques, improved quality of life, health, greater number of medications used, reduction of pharmacotherapeutic problems, and improvement in eating habits.

CONCLUSION

The pharmacotherapeutic follow-up promoted clinical and humanistic benefits, with improvement in quality of life and health.

摘要

背景

在胰岛素类似物司法化的背景下,缺乏评估药物治疗随访有效性的研究。

目的

评估在巴西一个城市中,通过司法裁决接受胰岛素类似物治疗的1型糖尿病患者进行药物治疗随访的临床和人文影响。

方法

通过药物治疗随访进行了一项前后类型的准实验研究。接受参与研究的患者在干预前后进行了血糖和血脂谱的实验室检查,并接受了五次药学咨询。此外,还分析了生活质量、健康状况、与胰岛素应用技术相关的知识和技能。

结果

28名患者参与了所有阶段。其中,大多数为女性(53.6%),平均年龄为32.8±11.6岁。干预后,血糖水平、血压降低,体重指数增加。此外,在胰岛素应用技术方面有了更多的知识和技能,生活质量、健康状况得到改善,使用的药物数量增加,药物治疗问题减少,饮食习惯得到改善。

结论

药物治疗随访带来了临床和人文益处,生活质量和健康状况得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a67b/9063359/8c97d9bb468d/13098_2022_835_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a67b/9063359/903cad750840/13098_2022_835_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a67b/9063359/8c97d9bb468d/13098_2022_835_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a67b/9063359/903cad750840/13098_2022_835_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a67b/9063359/8c97d9bb468d/13098_2022_835_Fig2_HTML.jpg

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Pharmacists Intervention Reduced Drug-Related Problems in the Treatment of Patients with Type 2 Diabetes Mellitus.药剂师干预减少了2型糖尿病患者治疗中与药物相关的问题。
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Disclosures: -.披露信息:无。
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Elucidating factors associated with non-adherence among Type 1 diabetes patients in primary care setting in Southeastern Brazil.阐明巴西东南部初级保健环境中 1 型糖尿病患者不遵医行为的相关因素。
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Pharmacotherapeutic empowerment and its effectiveness in glycemic control in patients with Diabetes Mellitus.药物治疗自主权及其在糖尿病患者血糖控制中的有效性。
Diabetes Metab Syndr. 2019 Jan-Feb;13(1):137-142. doi: 10.1016/j.dsx.2018.08.002. Epub 2018 Aug 3.
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Mechanisms of Insulin Action and Insulin Resistance.胰岛素作用机制和胰岛素抵抗。
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